Protein S and factor V in regulation of coagulation on platelet microparticles by activated protein C.

Sofia Somajo, Ruzica Livaja Koshiar, Eva Norström, Björn Dahlbäck

Research output: Contribution to journalArticlepeer-review

23 Citations (SciVal)

Abstract

Platelets are the main source of microparticles in plasma and the concentration of microparticles is increased in many diseases. As microparticles expose negatively charged phospholipids, they can bind and assemble the procoagulant enzyme-cofactor complexes. Our aim was to elucidate possible regulation of these complexes on microparticles by the anticoagulant protein C system.
Original languageEnglish
Pages (from-to)144-152
JournalThrombosis Research
Volume134
Issue number1
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Cardiac and Cardiovascular Systems

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