Pseudomyxoma peritonei: A review of 62 cases

S. van Ruth; Y. I.Z. Acherman; M. J. van de Vijver; A. A.M. Hart; V. J. Verwaal; F. A.N. Zoetmulder

doi:10.1016/S0748-7983(03)00149-5

Pseudomyxoma peritonei: A review of 62 cases

S. van Ruth, Y. I.Z. Acherman, M. J. van de Vijver, A. A.M. Hart, V. J. Verwaal, F. A.N. Zoetmulder

Antoni Van Leeuwenhoek Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than those with more focal proliferation (n = 14). Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.

Original language	English
Pages (from-to)	682-688
Journal	European Journal of Surgical Oncology
Volume	29
Issue number	8
DOIs	https://doi.org/10.1016/S0748-7983(03)00149-5
Publication status	Published - 2003 Oct
Externally published	Yes

Subject classification (UKÄ)

Cancer and Oncology

Free keywords

Disseminated peritoneal adenomucinosis
HIPEC
Pathology
Peritoneal mucinous carcinomatosis with intermediate or discordant features
Pseudomyxoma peritonei

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0748-7983(03)00149-5

Cite this

@article{4f3d4c7b1e73435fb24942a62804574e,

title = "Pseudomyxoma peritonei: A review of 62 cases",

abstract = "Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than those with more focal proliferation (n = 14). Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.",

keywords = "Disseminated peritoneal adenomucinosis, HIPEC, Pathology, Peritoneal mucinous carcinomatosis with intermediate or discordant features, Pseudomyxoma peritonei",

author = "{van Ruth}, S. and Acherman, {Y. I.Z.} and {van de Vijver}, {M. J.} and Hart, {A. A.M.} and Verwaal, {V. J.} and Zoetmulder, {F. A.N.}",

year = "2003",

month = oct,

doi = "10.1016/S0748-7983(03)00149-5",

language = "English",

volume = "29",

pages = "682--688",

journal = "European Journal of Surgical Oncology",

issn = "0748-7983",

publisher = "Elsevier",

number = "8",

}

TY - JOUR

T1 - Pseudomyxoma peritonei

T2 - A review of 62 cases

AU - van Ruth, S.

AU - Acherman, Y. I.Z.

AU - van de Vijver, M. J.

AU - Hart, A. A.M.

AU - Verwaal, V. J.

AU - Zoetmulder, F. A.N.

PY - 2003/10

Y1 - 2003/10

N2 - Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than those with more focal proliferation (n = 14). Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.

AB - Aim: Pseudomyxoma peritonei (PMP) is a rare disease characterized by the abundance of mucus in the abdomen without extra-peritoneal growth. Methods: Our patients with PMP have been treated with cytoreduction and hyperthermic intraperitoneal chemotherapy since 1996. The clinical and histopathological features of PMP and the relation of these features with disease-free interval and survival were assessed. Results: Sixty-two patients with PMP (24 M/38 F) were studied. Adenomatous mucosal changes were present in 31 patients. In females, the ovaries were normal in 5 patients and pseudomyxoma ovarii was present in 20 patients. Patients with minimal atypia and with 1% focal proliferation or less (n = 38) had a better survival (p = 0.0008) than those with more focal proliferation (n = 14). Conclusion: In most patients with PMP the appendix is affected; in females the ovaries are usually also involved. Focal proliferation appears to be a prognostic factor.

KW - Disseminated peritoneal adenomucinosis

KW - HIPEC

KW - Pathology

KW - Peritoneal mucinous carcinomatosis with intermediate or discordant features

KW - Pseudomyxoma peritonei

U2 - 10.1016/S0748-7983(03)00149-5

DO - 10.1016/S0748-7983(03)00149-5

M3 - Article

C2 - 14511618

AN - SCOPUS:0141954881

SN - 0748-7983

VL - 29

SP - 682

EP - 688

JO - European Journal of Surgical Oncology

JF - European Journal of Surgical Oncology

IS - 8

ER -

Pseudomyxoma peritonei: A review of 62 cases

Abstract

Subject classification (UKÄ)

Free keywords

UN SDGs

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Cite this