Quality-of-life after bile duct injury repaired by hepaticojejunostomy: a national cohort study

Christian Sturesson, Oskar Hemmingsson, Christopher Månsson, Per Sandström, Cecilia Strömberg, Helena Taflin, Jenny Rystedt

Research output: Contribution to journalArticlepeer-review


Objectives: Reports on quality-of-life (QoL) after bile duct injury (BDI) show conflicting results. The aim of this cohort study was to evaluate QoL stratified according to type of treatment. Methods: QoL assessment using the SF-36 (36-item short form health survey) questionnaire. Patients with post-cholecystectomy BDI needing hepaticojejunostomy (HJ) were compared to all other treatments (BDI repair) and to patients without BDI at cholecystectomy (controls). Results: Patients needing a HJ after BDI reported reduced long-term QoL irrespective of time for diagnosis and repair in both the physical (PCS; p <.001) and mental (MCS; p <.001) domain compared to both controls and patients with less severe BDI. QoL was comparable for BDI repair (n = 86) and controls (n = 192) in both PCS (p =.171) and MCS (p =.654). As a group, patients with BDI (n = 155) reported worse QoL than controls, in both the PCS (p <.001) and MCS (p =.012). Patients with a BDI detected intraoperatively (n = 124) reported better QoL than patients with a postoperative diagnosis. Patients with an immediate intraoperative repair (n = 99), including HJ, reported a better long-term QoL compared to patients subjected to a later procedure (n = 54). Conclusions: Patients with postoperative diagnosis and patients with BDIs needing biliary reconstruction with HJ both reported reduced long-term QoL.

Original languageEnglish
Pages (from-to)1087-1092
Number of pages6
JournalScandinavian Journal of Gastroenterology
Issue number9
Early online date2020 Jul 31
Publication statusPublished - 2020

Subject classification (UKÄ)

  • Surgery
  • Public Health, Global Health, Social Medicine and Epidemiology

Free keywords

  • BDI
  • bile duct injury
  • cholecystectomy
  • hepaticojejunostomy
  • Quality-of-life
  • SF-36


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