Quantitative analysis of circadian variation in atrial fibrillation frequency

Frida Sandberg, Andreas Bollman, Daniela Husser, Martin Stridh, Leif Sörnmo

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

Circadian variation in atrial fibrillation (AF) frequency
is explored in this paper by employing recent advances in
signal processing. Once the AF frequency has been estimated
and tracked by a hidden Markov model approach,
the resulting trend is analyzed for the purpose of detecting
and characterizing the presence of circadian variation.
With cosinor analysis, the results show that the shortterm
variations in AF frequency exceeds the variation that
may be attributed to circadian. Using the autocorrelation
method, circadian variation was detected in 13 of 18
ambulatory ECG recordings (Holter) acquired from patients
with long standing persistent AF. Using the ensemble
correlation method, the highest AF frequency usually occurred
during the afternoon, whereas the lowest usually
occurred during late night. It is concluded that circadian
variation is present in most patients with long standing
persistent AF but the short-term variation in AF frequency
is considerable.
Original languageEnglish
Title of host publication[Host publication title missing]
PublisherIEEE - Institute of Electrical and Electronics Engineers Inc.
Pages129-132
Volume36
Publication statusPublished - 2009
Event36th Annual Computers in Cardiology Conference, 2009 - Pk City, UT, Park City, UT, United States
Duration: 2009 Sept 132009 Sept 16
Conference number: 36

Publication series

Name
Volume36

Conference

Conference36th Annual Computers in Cardiology Conference, 2009
Abbreviated titleCinC 2009
Country/TerritoryUnited States
CityPark City, UT
Period2009/09/132009/09/16

Subject classification (UKÄ)

  • Electrical Engineering, Electronic Engineering, Information Engineering

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