Quantitative SPECT by attenuation correction of the projection set using transmission data: evaluation of a method

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Abstract

A method for measuring attenuation coefficients in single-photon emission tomography (SPECT) is described and evaluated, together with a method for attenuation correction using these measured attenuation coefficients. Build-up, caused by scattered photons, is corrected for by a simple substitution in the algorithms. Transmission studies are performed with a 99mTc- or 57Co flood source, and emission phantom studies with 99mTc line sources. The method is evaluated with variable but well-defined phantoms. The result is accurate attenuation coefficients for different densities, dimensions and geometries, and an accuracy of corrected emission activities of better than +/- 10% in most cases. The present limitations of the method for attenuation correction are discussed.
Original languageEnglish
Pages (from-to)587-594
JournalEuropean Journal Of Nuclear Medicine
Volume16
Issue number8-10
DOIs
Publication statusPublished - 1990

Subject classification (UKÄ)

  • Radiology and Medical Imaging

Free keywords

  • Attenuation correction
  • Build-up
  • Quantitative SPECT
  • Transmission measurement

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