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Abstract
The presence of paralytic shellfish poisoning toxins (PSTs) in drinking water resources has urged the development of simple and fast screening tools for drinking water surveillance. This article aims to validate
a quick test kit for freshwater PSTs detection. Preliminary estimates of the limit of detection (LODs)
were done for 5 PSPs variants, namely C1 toxin (a “C” toxin); GTX5(a Gonyautoxin); and neosaxitoxin,
dcSaxitoxin and saxitoxin (STX) and a mixture of C1 and saxitoxin. Duplicate samples and Blank/Control are used. In total 50 samples were tested plus 7 negative controls. Results show that clear estimated
LOD levels for all variants except for C1. Further validation for lower detection limits is recommended if
a lower concentration is of concern. Owing to cross-reactivity within the different derivatives, water operators/managers should be aware of certain false-negative risks to certain variants. Therefore, a thorough
understanding of the toxin profile in source water is necessary for its application.
a quick test kit for freshwater PSTs detection. Preliminary estimates of the limit of detection (LODs)
were done for 5 PSPs variants, namely C1 toxin (a “C” toxin); GTX5(a Gonyautoxin); and neosaxitoxin,
dcSaxitoxin and saxitoxin (STX) and a mixture of C1 and saxitoxin. Duplicate samples and Blank/Control are used. In total 50 samples were tested plus 7 negative controls. Results show that clear estimated
LOD levels for all variants except for C1. Further validation for lower detection limits is recommended if
a lower concentration is of concern. Owing to cross-reactivity within the different derivatives, water operators/managers should be aware of certain false-negative risks to certain variants. Therefore, a thorough
understanding of the toxin profile in source water is necessary for its application.
| Original language | English |
|---|---|
| Article number | 1 |
| Pages (from-to) | 23-29 |
| Journal | Vatten: tidskrift för vattenvård /Journal of Water Management and research |
| Volume | 1 |
| Issue number | 76 |
| Publication status | Published - 2020 Mar |
Subject classification (UKÄ)
- Water Treatment
Free keywords
- Saxitoxin
- quick test kit
- LFA
- detection limit
- validation
Fingerprint
Dive into the research topics of 'Rapid analysis methods for paralytic shellfish poisoning toxins (PSTs) monitoring in raw waters'. Together they form a unique fingerprint.Research output
- 1 Doctoral Thesis (compilation)
-
Managing Eutrophic Waters in Artificial Recharge Plants: Cyanotoxin risk in Swedish freshwaters
Li, J., 2020 Mar 27, Lund: Department of Water Resources Engineering, Lund Institute of Technology, Lund University. 81 p.Research output: Thesis › Doctoral Thesis (compilation)
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