Reappraisal of the regulation of lactococcal L-lactate dehydrogenase

Ed van Niel, Johan Palmfeldt, Rani Martin, Marco Paese, Bärbel Hahn-Hägerdal

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    Abstract

    Lactococcal lactate dehydrogenases (LDHs) are coregulated at the substrate level by at least two mechanisms: the fructose- 1,6-biphosphate/phosphate ratio and the NADH/NAD ratio. Among the Lactococcus lactis species, there are strains that are predominantly regulated by the first mechanism (e.g., strain 65.1) or by the second mechanism (e.g., strain NCDO 2118). A more complete model of the kinetics of the regulation of lactococcal LDH is discussed.
    Original languageEnglish
    Pages (from-to)1843-1846
    JournalApplied and Environmental Microbiology
    Volume70
    Issue number3
    DOIs
    Publication statusPublished - 2004

    Subject classification (UKÄ)

    • Industrial Biotechnology

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