Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis

J. Enrique Dominguez-Munoz, Roland Andersson, Sara Regnér, P. Hegyi, et al.

Research output: Contribution to journalReview articlepeer-review


Background: In collaboration with United European Gastroenterology, the working group on ‘Harmonizing diagnosis and treatment of chronic pancreatitis across Europe’ (HaPanEU) developed European guidelines for the management of chronic pancreatitis using an evidence-based approach. Methods: Recommendations of multidisciplinary review groups based on systematic literature reviews to answer predefined clinical questions are summarised. Recommendations are graded using the Grading of Recommendations Assessment, Development and Evaluation system. Results: Recommendations covered topics related to the clinical management of chronic pancreatitis: aetiology, diagnosis of chronic pancreatitis with imaging, diagnosis of pancreatic exocrine insufficiency, surgical therapy, medical therapy, endoscopic therapy, treatment of pancreatic pseudocysts, pancreatic pain, nutrition and malnutrition, diabetes mellitus and the natural course of the disease and quality of life. Conclusions: The HaPanEU/United European Gastroenterology guidelines provide evidence-based recommendations concerning key aspects of the medical and surgical management of chronic pancreatitis based on current available evidence. These recommendations should serve as a reference standard for existing management of the disease and as a guide for future clinical research. This article summarises the HaPanEU recommendations and statements.
Original languageEnglish
Pages (from-to)847-854
Number of pages8
Issue number8
Publication statusPublished - 2018 Dec

Subject classification (UKÄ)

  • Gastroenterology and Hepatology
  • Health Care Service and Management, Health Policy and Services and Health Economy

Free keywords

  • Chronic pancreatitis
  • Development and evaluation (GRADE)
  • Diabetes mellitus
  • Endoscopic therapy
  • Grading of recommendations assessment
  • Guidelines
  • Pain
  • Pancreatic exocrine insufficiency
  • Pseudocyst
  • Quality of life
  • analgesic agent
  • pancreas enzyme
  • analgesia
  • artificial embolization
  • calcification
  • chronic pancreatitis
  • conservative treatment
  • diabetes mellitus
  • dilated pancreatic duct
  • echography
  • endoscopic therapy
  • endoscopic ultrasonography
  • enzyme replacement
  • European
  • evidence based practice
  • exocrine pancreatic insufficiency
  • extracorporeal shock wave lithotripsy
  • false aneurysm
  • gastroenterologist
  • pancreatogenic diabetes
  • magnetic resonance cholangiopancreatography
  • malnutrition
  • nuclear magnetic resonance imaging
  • nutrition
  • nutritional assessment
  • practice guideline
  • pancreas disease
  • pancreas function test
  • pancreas pseudocyst
  • pancreas surgery
  • pancreatic duct
  • pancreatitis


Dive into the research topics of 'Recommendations from the United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis'. Together they form a unique fingerprint.

Cite this