Reduced field-of-view MRI using outer volume suppression for spinal cord diffusion imaging

B. J. Wilm, Jonas Svensson, A. Henning, K. P. Pruessmann, P. Boesiger, S. S. Kollias

Research output: Contribution to journalArticlepeer-review


A spin-echo single-shot echo-planar imaging (SS-EPI) technique with a reduced field of view (FOV) in the phase-encoding direction is presented that simultaneously reduces susceptibility effects and motion artifacts in diffusion-weighted (DW) imaging (DWI) of the spinal cord at a high field strength (3T). To minimize aliasing, an outer volume suppression (OVS) sequence was implemented. Effective fat suppression was achieved with the use of a slice-selection gradient-reversal technique. The OVS was optimized by numerical simulations with respect to T-1 relaxation times and B-1 variations. The optimized sequence was evaluated in vitro and in vivo. In simulations the optimized OVS showed suppression to < 0.25% and similar to 3% in an optimal and worst-case scenario, respectively. In vitro measurements showed a mean residual signal of < 0.95% +/- 0.42 for all suppressed areas. In vivo acquisition with 0.9 x 1.05 mm(2) in-plane resolution resulted in artifact-free images. The short imaging time of this technique makes it promising for clinical studies.
Original languageEnglish
Pages (from-to)625-630
JournalMagnetic Resonance in Medicine
Issue number3
Publication statusPublished - 2007

Subject classification (UKÄ)

  • Radiology, Nuclear Medicine and Medical Imaging

Free keywords

  • outer volume suppression
  • reduced FOV
  • spinal cord
  • diffusion imaging
  • DTI


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