Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells.

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45 Citations (SciVal)

Abstract

Regulation of mRNAs is one way to control protein levels and thereby important cellular processes such as growth, invasion and apoptosis. G3BPs constitute a family of mRNA-binding proteins, shown to be overexpressed in several cancer types, including breast, colon and pancreas cancer. G3BP has been reported to both stabilize and induce degradation of specific mRNAs.
Original languageEnglish
Article number156
JournalMolecular Cancer
Volume12
Issue number1
DOIs
Publication statusPublished - 2013

Subject classification (UKÄ)

  • Cancer and Oncology

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