Repairing the brain: Gene therapy

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2 Citations (SciVal)


In vivo gene therapy for neurodegenerative disorders has turned out to be a formidable challenge. It is a field not much older than twenty years, but we were many who would have predicted a much easier path towards the clinic using this treatment modality. For Parkinson's disease patients, this has meant a frustrating wait, seeing many promising therapies being forgotten after a few pre-clinical proof-of-concept studies. The reasons for this are both scientific and economical. However, this is slowly but surely changing and over the next two decades we will see a very exciting development in this field. In a foreseeable future, gene therapy will be a very natural component of many clinical therapies, not least in Parkinson's disease.

Original languageEnglish
Pages (from-to)S123-S130
JournalJournal of Parkinson's Disease
Issue numbers1
Publication statusPublished - 2018

Subject classification (UKÄ)

  • Neurology


  • Clinical trial
  • Dependovirus
  • Gene editing
  • Genetic therapy
  • Neuroprotection
  • Parkinson's disease
  • Rejuvenation


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