Research output per year
Research output per year
Sinja Kristiansen, Åke Svensson, Linda Drevin, Ola Forslund, Christian Torbrand, Carina Bjartling
Research output: Contribution to journal › Article › peer-review
Studies on risk factors for penile intraepithelial neo-plasia have been small in size, have not distinguished penile intraepithelial neoplasia from invasive cancer, and have relied on self-reported information. This study investigated risk factors for penile intraepithelial neoplasia in a cohort of 580 penile intraepithelial neoplasia cases and 3,436 controls using information from 7 Swedish registers. Cases with penile intraepithelial neoplasia had increased odds ratios (ORs) for inflammatory skin diseases (14.7, 95% CI 6.5-33.4) including lichen planus (12.0, 95% CI 3.0-48.0), indicating lichen planus to be an important risk factor. Increased ORs were also observed for diseases of the prepuce (4.0, 95% CI 2.2-7.4), immunosuppressive drugs (5.0, 95% CI 2.5-9.8), penile surgical procedures (4.8, 95% CI 2.2-10.8), balanitis (9.2, 95% CI 5.0-16.8), genital warts (9.9, 95% CI 4.3-22.7) and organ transplantation (7.0, 95% CI 2.4-20.8). This study demonstrates important risk factors for penile intraepithelial neoplasia, providing knowledge that can help prevent the development of penile cancer.
Original language | English |
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Pages (from-to) | 315-320 |
Number of pages | 6 |
Journal | Acta Dermato-Venereologica |
Volume | 99 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2019 |
Research output: Thesis › Doctoral Thesis (compilation)