Searching for WT1 target genes in leukemic cell lines

Helena Jernmark Nilsson

Searching for WT1 target genes in leukemic cell lines

Helena Jernmark Nilsson

Research output: Thesis › Doctoral Thesis (compilation)

150 Downloads (Pure)

Original language	English
Qualification	Doctor
Awarding Institution	Department of Laboratory Medicine
Supervisors/Advisors	Gullberg, Urban, Supervisor Malmros, Karina, Assistant supervisor Hansson, Markus, Assistant supervisor
Award date	2019 Oct 17
Place of Publication	Lund
Publisher	Lund University: Faculty of Medicine
ISBN (Print)	978-91-7619-832-2
Publication status	Published - 2019

Bibliographical note

Defence details
Date: 2019-10-17
Time: 09:00
Place: BMC I1345, Sölvegatan 19 i Lund
External reviewer(s)
Name: Åman, Pierre
Title: Ph.D., Professor
Affiliation: University of Gothenburg

Subject classification (UKÄ)

Hematology
Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

Avhandling i mall G5-slutFinal published version, 796 KB

3 Article

Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms' tumor gene 1 (WT1) protein in leukemic cells
Ullmark, T., Montano, G., Järvstråt, L., Jernmark Nilsson, H., Håkansson, E., Drott, K., Nilsson, B., Vidovic, K. & Gullberg, U., 2017 Jan 22, In: Biochemical and Biophysical Research Communications. 482, 4, p. 802–807 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
300 Downloads (Pure)
The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells
Nilsson, H. J., Montano, G., Ullmark, T., Lennartsson, A., Drott, K., Järvstråt, L., Nilsson, B., Vidovic, K. & Gullberg, U., 2017, In: Oncotarget. 8, 50, p. 87136-87150
Research output: Contribution to journal › Article › peer-review

Open Access
The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.
Montano, G., Ullmark, T., Jernmark Nilsson, H., Sodaro, G., Drott, K., Costanzo, P., Vidovic, K. & Gullberg, U., 2016, In: Leukemia Research: A Forum for Studies on Leukemia and Normal Hemopoiesis. 40, 1, p. 60-67
Research output: Contribution to journal › Article › peer-review

Open Access
File
329 Downloads (Pure)

Cite this

@phdthesis{21d8aacde7c7409cb3ad32ace0fd9e13,

title = "Searching for WT1 target genes in leukemic cell lines",

keywords = "WT1, Wilms' tumor gene 1, AML, target gene, ZNF224, IRF8, QPRT, NAB2, FSCN1",

author = "{Jernmark Nilsson}, Helena",

note = "Defence details Date: 2019-10-17 Time: 09:00 Place: BMC I1345, S{\"o}lvegatan 19 i Lund External reviewer(s) Name: {\AA}man, Pierre Title: Ph.D., Professor Affiliation: University of Gothenburg",

year = "2019",

language = "English",

isbn = "978-91-7619-832-2",

series = "Lund University, Faculty of Medicine Doctoral Dissertation Series",

publisher = "Lund University: Faculty of Medicine",

number = "103",

type = "Doctoral Thesis (compilation)",

school = "Department of Laboratory Medicine",

}

TY - THES

T1 - Searching for WT1 target genes in leukemic cell lines

AU - Jernmark Nilsson, Helena

N1 - Defence details Date: 2019-10-17 Time: 09:00 Place: BMC I1345, Sölvegatan 19 i Lund External reviewer(s) Name: Åman, Pierre Title: Ph.D., Professor Affiliation: University of Gothenburg

PY - 2019

Y1 - 2019

KW - WT1, Wilms' tumor gene 1, AML, target gene, ZNF224, IRF8, QPRT, NAB2, FSCN1

M3 - Doctoral Thesis (compilation)

SN - 978-91-7619-832-2

T3 - Lund University, Faculty of Medicine Doctoral Dissertation Series

PB - Lund University: Faculty of Medicine

CY - Lund

ER -

Searching for WT1 target genes in leukemic cell lines

Bibliographical note

Subject classification (UKÄ)

UN SDGs

Access to Document

Research output

Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms' tumor gene 1 (WT1) protein in leukemic cells

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells

The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.

Cite this