Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.

Frida Renström; Robert Koivula; Tibor V Varga; Göran Hallmans; Hindrik Mulder; Jose C Florez; Frank B Hu; Paul Franks

doi:10.1007/s00125-015-3533-8

Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.

Frida Renström, Robert Koivula, Tibor V Varga, Göran Hallmans, Hindrik Mulder, Jose C Florez, Frank B Hu, Paul Franks

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Abstract

The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.

Original language	English
Pages (from-to)	997-1005
Journal	Diabetologia
Volume	58
Issue number	5
DOIs	https://doi.org/10.1007/s00125-015-3533-8
Publication status	Published - 2015

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SDG 3 Good Health and Well-being

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Endocrinology and Diabetes

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10.1007/s00125-015-3533-8

http://www.ncbi.nlm.nih.gov/pubmed/25707907?dopt=Abstract

Cite this

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title = "Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.",

abstract = "The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.",

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AU - Renström, Frida

AU - Koivula, Robert

AU - V Varga, Tibor

AU - Hallmans, Göran

AU - Mulder, Hindrik

AU - Florez, Jose C

AU - Hu, Frank B

AU - Franks, Paul

PY - 2015

Y1 - 2015

N2 - The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.

AB - The association of single nucleotide polymorphisms (SNPs) proximal to CRY2 and MTNR1B with fasting glucose is well established. CRY1/2 and MTNR1B encode proteins that regulate circadian rhythmicity and influence energy metabolism. Here we tested whether season modified the relationship of these loci with blood glucose concentration.

UR - https://www.scopus.com/pages/publications/84939981613

U2 - 10.1007/s00125-015-3533-8

DO - 10.1007/s00125-015-3533-8

M3 - Article

C2 - 25707907

SN - 1432-0428

VL - 58

SP - 997

EP - 1005

JO - Diabetologia

JF - Diabetologia

IS - 5

ER -

Season-dependent associations of circadian rhythm-regulating loci (CRY1, CRY2 and MTNR1B) and glucose homeostasis: the GLACIER Study.

Abstract

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