@article{733304beb79546828916cd1774ecdcab,
title = "Secondhand Smoke Exposure Causes Bronchial Hyperreactivity via Transcriptionally Upregulated Endothelin and 5-hydroxytryptamine 2A Receptors.",
abstract = "Cigarette smoke exposure is strongly associated with airway hyperreactivity (AHR) which is the main characteristic seen in asthma. The intracellular MAPK signaling pathways are suggested to be associated with the airway damage to the AHR. In the present study, we hypothesize that secondhand cigarette smoke (SHS) exposure upregulates the bronchial contractile receptors via activation of the Raf/ERK/MAPK pathway.",
author = "Lei Cao and Yaping Zhang and Yong-Xiao Cao and Lars Edvinsson and Cang-Bao Xu",
year = "2012",
doi = "10.1371/journal.pone.0044170",
language = "English",
volume = "7",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science (PLoS)",
number = "8",
}