SENSITIVITY ANALYSIS OF THE ICRP BIOKINETIC MODEL PREDICTING THE ACTIVITY OF GD IN LUNGS AND 24-HOUR EXCRETION SAMPLES

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Abstract

148Gd may contribute to around 50% of the dose from inhalation in case of an accident at the European Spallation Source. Methods for its detection have been developed. They rely on biokinetic models predicting activities of the gamma emitters 146Gd (T1/2= 48.3 d) and 153Gd (T1/2= 240.4 d) as tracers in the lungs, urine, and faeces. The optimal choice of model parameters and associated uncertainties, which propagate to the estimates of the minimum detectable activity of 148Gd (T1/2= 84±4 y), have yet to be systematically investigated. This work presents a step in this direction. The authors have implemented the ICRP biokinetic model for Gd and performed a sensitivity analysis of the model to identify the most influential parameters. They will use this knowledge in subsequent uncertainty analysis and determination of the optimal measurement time window.
Original languageEnglish
Title of host publicationKaunas University of Technology
PublisherKaunas University of Technology
Pages55-59
Publication statusPublished - 2023 Nov 11

Publication series

NameMEDICAL PHYSICS IN THE BALTIC STATES
PublisherKaunas University of Technology
ISSN (Print)1822-5721

Subject classification (UKÄ)

  • Physical Sciences
  • Medical and Health Sciences
  • Radiology, Nuclear Medicine and Medical Imaging

Free keywords

  • ESS
  • radioactive aerosols
  • internal dosimetry

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