Abstract
A granulomatous alveolitis, with multinuclear cell formation combined with an eosinophilic peribronchiolitis, was achieved in rats by intratracheal administration of sephadex beads (G-200, Pharmacia, Sweden). The pattern of inflammation and the degree of postgranulomatous fibrosis were substantially dampened when the particles were dispersed by ultrasonification. The animals were analyzed with bronchoalveolar lavage and tissue morphology.
| Original language | English |
|---|---|
| Pages (from-to) | 73-78 |
| Journal | American Journal of Industrial Medicine |
| Volume | 25 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1994 |
| Externally published | Yes |
Subject classification (UKÄ)
- Cell and Molecular Biology
- Respiratory Medicine and Allergy
Free keywords
- bronchoalveolar lavage
- allergic alveolitis
- eosinophils
- lymphocytes
- sephadex
- organic dusts