Abstract
To evaluate whether cytokines are altered in peripheral blood of rats transgenic for the human Huntington´s disease mutation we investigated serum levels of GRO/KC, IL-1β, IL-13 and TNF-α at a symptomatic stage at 12 months of age. Overall serum levels of these cytokines were not significantly changed between transgenic HD rats and controls. Moreover, we observed a high interindividual variability. Our results indicate that these cytokines will be difficult to pursue as biomarkers in at least this rat model of HD.
| Original language | English |
|---|---|
| Article number | RRN1190 |
| Journal | PLoS Currents |
| Volume | 2 |
| DOIs | |
| Publication status | Published - 2010 |
Bibliographical note
The information about affiliations in this record was updated in December 2015.The record was previously connected to the following departments: Neuronal Survival (013212041)
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Subject classification (UKÄ)
- Neurosciences
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