Serum thymidine kinase in congenital dyserythropoietic anaemia type III

H. Sandstrom; A. Wahlin; M. Eriksson; I. Bergström

doi:10.1111/j.1365-2141.1994.tb08334.x

Serum thymidine kinase in congenital dyserythropoietic anaemia type III

H. Sandstrom, A. Wahlin, M. Eriksson, I. Bergström

Norrland University Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

Serum thymidine kinase (TK) was determined in a family with congenital dyserythropoietic anaemia type m (CDA, type III). 20 patients and 10 of their healthy siblings were investigated. Elevated TK was found in all 20 patients (median 56.2 U) but their healthy siblings had normal values (median 2.65 U). We suggest that determination of TK should be used for discrimination between healthy siblings and individuals affected by CDA type III when bone marrow examination is not suitable.

Original language	English
Pages (from-to)	653-654
Journal	British Journal of Haematology
Volume	87
Issue number	3
DOIs	https://doi.org/10.1111/j.1365-2141.1994.tb08334.x
Publication status	Published - 1994
Externally published	Yes

Subject classification (UKÄ)

Hematology

Free keywords

Autosomal dominant
CDA type III
Haemolytic anaemia
Thymidine kinase

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10.1111/j.1365-2141.1994.tb08334.x

Cite this

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title = "Serum thymidine kinase in congenital dyserythropoietic anaemia type III",

abstract = "Serum thymidine kinase (TK) was determined in a family with congenital dyserythropoietic anaemia type m (CDA, type III). 20 patients and 10 of their healthy siblings were investigated. Elevated TK was found in all 20 patients (median 56.2 U) but their healthy siblings had normal values (median 2.65 U). We suggest that determination of TK should be used for discrimination between healthy siblings and individuals affected by CDA type III when bone marrow examination is not suitable.",

keywords = "Autosomal dominant, CDA type III, Haemolytic anaemia, Thymidine kinase",

author = "H. Sandstrom and A. Wahlin and M. Eriksson and I. Bergstr{\"o}m",

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language = "English",

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AU - Sandstrom, H.

AU - Wahlin, A.

AU - Eriksson, M.

AU - Bergström, I.

PY - 1994

Y1 - 1994

N2 - Serum thymidine kinase (TK) was determined in a family with congenital dyserythropoietic anaemia type m (CDA, type III). 20 patients and 10 of their healthy siblings were investigated. Elevated TK was found in all 20 patients (median 56.2 U) but their healthy siblings had normal values (median 2.65 U). We suggest that determination of TK should be used for discrimination between healthy siblings and individuals affected by CDA type III when bone marrow examination is not suitable.

AB - Serum thymidine kinase (TK) was determined in a family with congenital dyserythropoietic anaemia type m (CDA, type III). 20 patients and 10 of their healthy siblings were investigated. Elevated TK was found in all 20 patients (median 56.2 U) but their healthy siblings had normal values (median 2.65 U). We suggest that determination of TK should be used for discrimination between healthy siblings and individuals affected by CDA type III when bone marrow examination is not suitable.

KW - Autosomal dominant

KW - CDA type III

KW - Haemolytic anaemia

KW - Thymidine kinase

U2 - 10.1111/j.1365-2141.1994.tb08334.x

DO - 10.1111/j.1365-2141.1994.tb08334.x

M3 - Article

C2 - 7993814

AN - SCOPUS:0028322296

SN - 0007-1048

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EP - 654

JO - British Journal of Haematology

JF - British Journal of Haematology

IS - 3

ER -

Serum thymidine kinase in congenital dyserythropoietic anaemia type III

Abstract

Subject classification (UKÄ)

Free keywords

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