Sigmoidins J and K, two new prenylated isoflavonoids from Erythrina sigmoidea

Augustine E Nkengfack; Timothee W Vouffo; Juliette C Vardamides; Z Tanee Fomum; Ola Bergendorff; Olov Sterner

doi:10.1021/np50110a008

Sigmoidins J and K, two new prenylated isoflavonoids from Erythrina sigmoidea

Augustine E Nkengfack, Timothee W Vouffo, Juliette C Vardamides, Z Tanee Fomum, Ola Bergendorff, Olov Sterner

Research output: Contribution to journal › Article › peer-review

Abstract

In addition to the two known compounds neotautenol [2] and erythrinassinate B [4], two new compounds, an isoflavanone named sigmoidin J [1] and a coumestan derivative named sigmoidin K [3], have been isolated and characterized from the root bark of the Cameroonian medicinal plant Erythrina sigmoidea. Their structures have been established as 7, 4'-dihydroxy-2',5'-dimethoxy-6'(gamma, gamma-dimethylally)isoflavanone [1] and 3,9-dihydroxy-2,10-(gamma, gamma dimethylallyl) coumestan [3], respectively, by spectroscopic techniques and from chemical evidence.

Original language	English
Pages (from-to)	1172-1177
Journal	Journal of Natural Products
Volume	57
Issue number	8
DOIs	https://doi.org/10.1021/np50110a008
Publication status	Published - 1994

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)

Subject classification (UKÄ)

Dermatology and Venereal Diseases

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10.1021/np50110a008

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title = "Sigmoidins J and K, two new prenylated isoflavonoids from Erythrina sigmoidea",

abstract = "In addition to the two known compounds neotautenol [2] and erythrinassinate B [4], two new compounds, an isoflavanone named sigmoidin J [1] and a coumestan derivative named sigmoidin K [3], have been isolated and characterized from the root bark of the Cameroonian medicinal plant Erythrina sigmoidea. Their structures have been established as 7, 4'-dihydroxy-2',5'-dimethoxy-6'(gamma, gamma-dimethylally)isoflavanone [1] and 3,9-dihydroxy-2,10-(gamma, gamma dimethylallyl) coumestan [3], respectively, by spectroscopic techniques and from chemical evidence.",

author = "Nkengfack, {Augustine E} and Vouffo, {Timothee W} and Vardamides, {Juliette C} and Fomum, {Z Tanee} and Ola Bergendorff and Olov Sterner",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)",

year = "1994",

doi = "10.1021/np50110a008",

language = "English",

volume = "57",

pages = "1172--1177",

journal = "Journal of Natural Products",

issn = "0163-3864",

publisher = "The American Chemical Society (ACS)",

number = "8",

}

TY - JOUR

T1 - Sigmoidins J and K, two new prenylated isoflavonoids from Erythrina sigmoidea

AU - Nkengfack, Augustine E

AU - Vouffo, Timothee W

AU - Vardamides, Juliette C

AU - Fomum, Z Tanee

AU - Bergendorff, Ola

AU - Sterner, Olov

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)

PY - 1994

Y1 - 1994

N2 - In addition to the two known compounds neotautenol [2] and erythrinassinate B [4], two new compounds, an isoflavanone named sigmoidin J [1] and a coumestan derivative named sigmoidin K [3], have been isolated and characterized from the root bark of the Cameroonian medicinal plant Erythrina sigmoidea. Their structures have been established as 7, 4'-dihydroxy-2',5'-dimethoxy-6'(gamma, gamma-dimethylally)isoflavanone [1] and 3,9-dihydroxy-2,10-(gamma, gamma dimethylallyl) coumestan [3], respectively, by spectroscopic techniques and from chemical evidence.

AB - In addition to the two known compounds neotautenol [2] and erythrinassinate B [4], two new compounds, an isoflavanone named sigmoidin J [1] and a coumestan derivative named sigmoidin K [3], have been isolated and characterized from the root bark of the Cameroonian medicinal plant Erythrina sigmoidea. Their structures have been established as 7, 4'-dihydroxy-2',5'-dimethoxy-6'(gamma, gamma-dimethylally)isoflavanone [1] and 3,9-dihydroxy-2,10-(gamma, gamma dimethylallyl) coumestan [3], respectively, by spectroscopic techniques and from chemical evidence.

U2 - 10.1021/np50110a008

DO - 10.1021/np50110a008

M3 - Article

SN - 0163-3864

VL - 57

SP - 1172

EP - 1177

JO - Journal of Natural Products

JF - Journal of Natural Products

IS - 8

ER -

Sigmoidins J and K, two new prenylated isoflavonoids from Erythrina sigmoidea

Abstract

Bibliographical note

Subject classification (UKÄ)

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