Silicon sieve electrodes for neural implants - in vitro characterization & in vivo recordings

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

An in vitro model was developed to characterize the electrical properties of silicon microfabricated recording electrodes, using a Cu-wire mimicing a neural signal source. Phosphorous doped electrodes were used to achieve an all silicon device. The model was used to study signal amplitude as a function of distance between the electrode surface and the signal source. Signal crosstalk to neighbouring electrodes on the chips were recorded. The crosstalk was found to be 6 dB using an external reference electrode. Improvements were accomplished with an on chip reference electrode giving an amplitude crosstalk suppression of 20 dB. It was found that the amplitude decreased by a factor of 2 at a distance of 50 μm between the electrode surface and the signal source. Sieve electrodes were also implanted in the rat sciatic nerve and following a 10 week nerve regeneration period the dorsal and ventral (L5) roots in the spinal cord were stimulated. Compound action potentials were recorded via the chip. Lower leg muscle contraction activity was also induced by stimulating the regenerated sciatic nerve via the sieve electrode.

Original languageEnglish
Title of host publicationProcceedings of the 20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Subtitle of host publication Biomedical Engineering Towards the Year 2000 and Beyond
PublisherIEEE - Institute of Electrical and Electronics Engineers Inc.
Pages2225-2228
Volume20
ISBN (Print)0-7803-5164-9
DOIs
Publication statusPublished - 1998 Dec 1
Event20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Biomedical Engineering Towards the Year 2000 and Beyond - Hongkong, China
Duration: 1998 Nov 1 → …

Conference

Conference20th Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Country/TerritoryChina
CityHongkong
Period1998/11/01 → …

Subject classification (UKÄ)

  • Medical Biotechnology

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