Slow light for deep tissue imaging with ultrasound modulation

Huiliang Zhang; Mahmood Sabooni; Lars Rippe; Chulhong Kim; Stefan Kröll; Lihong V. Wang; Philip R. Hemmer

doi:10.1063/1.3696307

Slow light for deep tissue imaging with ultrasound modulation

Huiliang Zhang, Mahmood Sabooni, Lars Rippe, Chulhong Kim, Stefan Kröll, Lihong V. Wang, Philip R. Hemmer

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Abstract

Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3696307]

Original language	English
Journal	Applied Physics Letters
Volume	100
Issue number	13
DOIs	https://doi.org/10.1063/1.3696307
Publication status	Published - 2012

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Atom and Molecular Physics and Optics

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10.1063/1.3696307

Zhang2012a

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title = "Slow light for deep tissue imaging with ultrasound modulation",

abstract = "Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3696307]",

author = "Huiliang Zhang and Mahmood Sabooni and Lars Rippe and Chulhong Kim and Stefan Kr{\"o}ll and Wang, {Lihong V.} and Hemmer, {Philip R.}",

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T1 - Slow light for deep tissue imaging with ultrasound modulation

AU - Zhang, Huiliang

AU - Sabooni, Mahmood

AU - Rippe, Lars

AU - Kim, Chulhong

AU - Kröll, Stefan

AU - Wang, Lihong V.

AU - Hemmer, Philip R.

PY - 2012

Y1 - 2012

N2 - Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3696307]

AB - Slow light has been extensively studied for applications ranging from optical delay lines to single photon quantum storage. Here, we show that the time delay of slow-light significantly improves the performance of the narrowband spectral filters needed to optically detect ultrasound from deep inside highly scattering tissue. We demonstrate this capability with a 9 cm thick tissue phantom, having 10 cm(-1) reduced scattering coefficient, and achieve an unprecedented background-free signal. Based on the data, we project real time imaging at video rates in even thicker phantoms and possibly deep enough into real tissue for clinical applications like early cancer detection. VC 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.3696307]

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SN - 0003-6951

VL - 100

JO - Applied Physics Letters

JF - Applied Physics Letters

IS - 13

ER -

Slow light for deep tissue imaging with ultrasound modulation

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Subject classification (UKÄ)

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