Sorting of biomolecules via microdevices

Chia Fu Chou, Robert H. Austin, Olgica Bakajin, Judith A. Castelino, Shirley S. Chan, Edward C. Cox, Harold Craighead, Nicholas Darton, Thomas Duke, Jongyoon Han, Jonas O. Tegenfeldt, Steve Turner

Research output: Contribution to conferencePaper, not in proceedingpeer-review

Abstract

Micro and nano fabrication techniques have provided an unprecedented opportunity to create a designed world in which separation and fractionation technologies which normally occur on the macroscopic scale can be optimized by designing structures which utilize the basic physics of the process, or new processes can be realized by building structures which normally do not exist without external design. Since microfabrication is exceedingly sophisticated in its development, it is possible to design and construct highly creative microdevices which allow one to probe specific aspects of a biological objects. We give examples of uses of micro and nano fabrication which as opposed to simply shrinking the size of the vessels or tubes used in macroscopic lab environments, utilize our understanding the physics of the process to take advantage of fabrication technologies.

Original languageEnglish
Pages14-19
Number of pages6
Publication statusPublished - 1999 Dec 1
Externally publishedYes
Event1999 IEEE International Devices Meeting (IEDM) - Washington, DC, USA
Duration: 1999 Dec 51999 Dec 8

Conference

Conference1999 IEEE International Devices Meeting (IEDM)
CityWashington, DC, USA
Period1999/12/051999/12/08

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