Specific conditions for enhancement of lipoprotein lipase activity by platelets

Peter Nilsson-Ehle; Arlene S Garfinkel; Michael C Schotz

doi:10.1016/0024-3205(75)90054-5

Specific conditions for enhancement of lipoprotein lipase activity by platelets

Peter Nilsson-Ehle, Arlene S Garfinkel, Michael C Schotz

Division of Clinical Chemistry and Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

Homogenates of human blood platelets, but not of red blood cells, have been found to stimulate lipoprotein lipase activity only when assayed against an emulsified triglyceride substrate sonicated for a short period of time. The degree of stimulation was inversely related to the time of sonication of the substrate. Using chylomicrons as substrate no stimulation of lipoprotein lipase activity by platelet homogenate was seen.

Original language	English
Pages (from-to)	1703-1709
Journal	Life Sciences
Volume	16
Issue number	11
DOIs	https://doi.org/10.1016/0024-3205(75)90054-5
Publication status	Published - 1975

Subject classification (UKÄ)

Pharmacology and Toxicology
Medicinal Chemistry

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10.1016/0024-3205(75)90054-5

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@article{4abc1a5fb7e140bb9aec7b764f5f7cd1,

title = "Specific conditions for enhancement of lipoprotein lipase activity by platelets",

abstract = "Homogenates of human blood platelets, but not of red blood cells, have been found to stimulate lipoprotein lipase activity only when assayed against an emulsified triglyceride substrate sonicated for a short period of time. The degree of stimulation was inversely related to the time of sonication of the substrate. Using chylomicrons as substrate no stimulation of lipoprotein lipase activity by platelet homogenate was seen.",

author = "Peter Nilsson-Ehle and Garfinkel, {Arlene S} and Schotz, {Michael C}",

year = "1975",

doi = "10.1016/0024-3205(75)90054-5",

language = "English",

volume = "16",

pages = "1703--1709",

journal = "Life Sciences",

issn = "1879-0631",

publisher = "Elsevier",

number = "11",

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TY - JOUR

T1 - Specific conditions for enhancement of lipoprotein lipase activity by platelets

AU - Nilsson-Ehle, Peter

AU - Garfinkel, Arlene S

AU - Schotz, Michael C

PY - 1975

Y1 - 1975

N2 - Homogenates of human blood platelets, but not of red blood cells, have been found to stimulate lipoprotein lipase activity only when assayed against an emulsified triglyceride substrate sonicated for a short period of time. The degree of stimulation was inversely related to the time of sonication of the substrate. Using chylomicrons as substrate no stimulation of lipoprotein lipase activity by platelet homogenate was seen.

AB - Homogenates of human blood platelets, but not of red blood cells, have been found to stimulate lipoprotein lipase activity only when assayed against an emulsified triglyceride substrate sonicated for a short period of time. The degree of stimulation was inversely related to the time of sonication of the substrate. Using chylomicrons as substrate no stimulation of lipoprotein lipase activity by platelet homogenate was seen.

U2 - 10.1016/0024-3205(75)90054-5

DO - 10.1016/0024-3205(75)90054-5

M3 - Article

SN - 1879-0631

VL - 16

SP - 1703

EP - 1709

JO - Life Sciences

JF - Life Sciences

IS - 11

ER -

Specific conditions for enhancement of lipoprotein lipase activity by platelets

Abstract

Subject classification (UKÄ)

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