Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.

Hamed Emami; Parmanand Singh; Megan MacNabb; Esad Vucic; Zachary Lavender; James H F Rudd; Zahi A Fayad; Joshua Lehrer-Graiwer; Magnus Korsgren; Amparo L Figueroa; Jill Fredrickson; Barry Rubin; Udo Hoffmann; Quynh A Truong; James K Min; Amos Baruch; Khurram Nasir; Matthias Nahrendorf; Ahmed Tawakol

doi:10.1016/j.jcmg.2014.10.009

Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.

Hamed Emami, Parmanand Singh, Megan MacNabb, Esad Vucic, Zachary Lavender, James H F Rudd, Zahi A Fayad, Joshua Lehrer-Graiwer, Magnus Korsgren, Amparo L Figueroa, Jill Fredrickson, Barry Rubin, Udo Hoffmann, Quynh A Truong, James K Min, Amos Baruch, Khurram Nasir, Matthias Nahrendorf, Ahmed Tawakol

Division of Clinical Chemistry and Pharmacology

Research output: Contribution to journal › Article › peer-review

Abstract

This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory remodeling and whether splenic activity independently predicts the risk of cardiovascular disease (CVD) events.

Original language	English
Pages (from-to)	121-130
Journal	JACC: Cardiovascular Imaging
Volume	8
Issue number	2
DOIs	https://doi.org/10.1016/j.jcmg.2014.10.009
Publication status	Published - 2015

Subject classification (UKÄ)

Pharmacology and Toxicology
Medicinal Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jcmg.2014.10.009

http://www.ncbi.nlm.nih.gov/pubmed/25577441?dopt=Abstract

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Emami, H., Singh, P., MacNabb, M., Vucic, E., Lavender, Z., Rudd, J. H. F., Fayad, Z. A., Lehrer-Graiwer, J., Korsgren, M., Figueroa, A. L., Fredrickson, J., Rubin, B., Hoffmann, U., Truong, Q. A., Min, J. K., Baruch, A., Nasir, K., Nahrendorf, M., & Tawakol, A. (2015). Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans. JACC: Cardiovascular Imaging, 8(2), 121-130. https://doi.org/10.1016/j.jcmg.2014.10.009

@article{a8e989f8be1749e3bb69031648f1878a,

title = "Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.",

abstract = "This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory remodeling and whether splenic activity independently predicts the risk of cardiovascular disease (CVD) events.",

author = "Hamed Emami and Parmanand Singh and Megan MacNabb and Esad Vucic and Zachary Lavender and Rudd, {James H F} and Fayad, {Zahi A} and Joshua Lehrer-Graiwer and Magnus Korsgren and Figueroa, {Amparo L} and Jill Fredrickson and Barry Rubin and Udo Hoffmann and Truong, {Quynh A} and Min, {James K} and Amos Baruch and Khurram Nasir and Matthias Nahrendorf and Ahmed Tawakol",

year = "2015",

doi = "10.1016/j.jcmg.2014.10.009",

language = "English",

volume = "8",

pages = "121--130",

journal = "JACC: Cardiovascular Imaging",

issn = "1876-7591",

publisher = "Elsevier",

number = "2",

}

Emami, H, Singh, P, MacNabb, M, Vucic, E, Lavender, Z, Rudd, JHF, Fayad, ZA, Lehrer-Graiwer, J, Korsgren, M, Figueroa, AL, Fredrickson, J, Rubin, B, Hoffmann, U, Truong, QA, Min, JK, Baruch, A, Nasir, K, Nahrendorf, M & Tawakol, A 2015, 'Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.', JACC: Cardiovascular Imaging, vol. 8, no. 2, pp. 121-130. https://doi.org/10.1016/j.jcmg.2014.10.009

TY - JOUR

T1 - Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.

AU - Emami, Hamed

AU - Singh, Parmanand

AU - MacNabb, Megan

AU - Vucic, Esad

AU - Lavender, Zachary

AU - Rudd, James H F

AU - Fayad, Zahi A

AU - Lehrer-Graiwer, Joshua

AU - Korsgren, Magnus

AU - Figueroa, Amparo L

AU - Fredrickson, Jill

AU - Rubin, Barry

AU - Hoffmann, Udo

AU - Truong, Quynh A

AU - Min, James K

AU - Baruch, Amos

AU - Nasir, Khurram

AU - Nahrendorf, Matthias

AU - Tawakol, Ahmed

PY - 2015

Y1 - 2015

N2 - This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory remodeling and whether splenic activity independently predicts the risk of cardiovascular disease (CVD) events.

AB - This study sought to determine whether splenic activation after acute coronary syndrome (ACS) is linked to leukocyte proinflammatory remodeling and whether splenic activity independently predicts the risk of cardiovascular disease (CVD) events.

U2 - 10.1016/j.jcmg.2014.10.009

DO - 10.1016/j.jcmg.2014.10.009

M3 - Article

SN - 1876-7591

VL - 8

SP - 121

EP - 130

JO - JACC: Cardiovascular Imaging

JF - JACC: Cardiovascular Imaging

IS - 2

ER -

Splenic Metabolic Activity Predicts Risk of Future Cardiovascular Events: Demonstration of a Cardiosplenic Axis in Humans.

Abstract

Subject classification (UKÄ)

UN SDGs

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