Abstract
Foscarnet has been shown to inhibit the proliferation of human T and B lymphocytes in vitro. The production of lymphokines was more strongly affected than the DNA synthesis. Monocyte function was only partly inhibited by the highest foscarnet concentration tried. The influence of foscarnet on the immune system could explain the beneficial effect observed in patients with HBV-related fulminant hepatitis treated with foscarnet.
| Original language | English |
|---|---|
| Pages (from-to) | 421-427 |
| Journal | Progress in Clinical and Biological Research |
| Volume | 364 |
| Publication status | Published - 1991 Jan 1 |
Subject classification (UKÄ)
- Microbiology in the medical area
