Successfully achieving target weight loss influences subsequent maintenance of lower weight and dropout from treatment

Tomohide Yamada, Kazuo Hara, Akiko Kishi Svensson, Nobuhiro Shojima, Jun Hosoe, Minaka Iwasaki, Toshimasa Yamauchi, Takashi Kadowaki

Research output: Contribution to journalArticlepeer-review


OBJECTIVES: The influence of the amount and rate of weight loss on subsequently regaining weight and dropout from treatment in severely obese patients targeting 5% weight loss was investigated.

METHODS: A total of 120 consecutive hospital patients with severe obesity (BMI: 42 ± 9 kg/m(2) ) participated in an inpatient program targeting 5% weight loss that involved goal setting, charting weight four times daily, and diet and exercise. They were followed after discharge to assess subsequent regaining of weight and dropout.

RESULTS: Mean weight loss was 4.9 ± 2.4% after a mean of 19 days in the hospital, and 43% of the patients achieved the target weight loss (>5%). Over the median 2-year follow-up period, greater than 5% in-hospital weight loss was associated with a significantly lower risk of regaining weight after adjustment for various factors (>5% to ≤7% loss: hazard ratio 0.30 [0.11-0.85] for regaining all of the lost weight and 0.32 [0.13-0.78] for regaining half of the lost weight). No significant relation between the amount or rate of weight loss and dropout from subsequent outpatient treatment was seen.

CONCLUSIONS: Successfully achieving the target weight loss in a comprehensive program predicts subsequent maintenance of lower weight without increasing the risk of dropout. Successful in-hospital weight loss might increase the motivation of obese patients.

Original languageEnglish
Pages (from-to)183-91
Number of pages9
Issue number1
Publication statusPublished - 2015 Jan
Externally publishedYes

Bibliographical note

© 2014 The Obesity Society.

Subject classification (UKÄ)

  • Family Medicine

Free keywords

  • Adult
  • Aged
  • Behavior Therapy
  • Body Mass Index
  • Body Weight
  • Diet
  • Exercise Therapy
  • Female
  • Goals
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Motivation
  • Obesity, Morbid/complications
  • Patient Dropouts/psychology
  • Treatment Outcome
  • Weight Loss/physiology
  • Weight Reduction Programs


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