The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans

R Yhede; Kaj Blennow; A Forsman; Henrik Anckarsäter

doi:10.1007/s00702-003-0073-z

The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans

R Yhede, Kaj Blennow, A Forsman, Henrik Anckarsäter

Department of Clinical Sciences, Malmö

Research output: Contribution to journal › Article › peer-review

Abstract

Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.

Original language	English
Pages (from-to)	1369-1373
Journal	Journal of Neural Transmission
Volume	110
Issue number	12
DOIs	https://doi.org/10.1007/s00702-003-0073-z
Publication status	Published - 2003

Subject classification (UKÄ)

Neurology

Free keywords

Dopamine
serotonin
thyroxine
triiodothyroxine

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10.1007/s00702-003-0073-z

Cite this

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title = "The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans",

abstract = "Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.",

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AU - Forsman, A

AU - Anckarsäter, Henrik

PY - 2003

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N2 - Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.

AB - Do the CNS monoaminergic (MA) systems regulate thyroid hormone metabolism in humans? In 23 unmedicated, male, violent offenders without signs of thyroid disease, we found positive correlations between the catecholaminergic CSF metabolites HVA and MHPG and the peripheral T3/T4 ratio (rho=0.55, p=0.010 and 0.51, p=0.018), indicating that increased activity in the brain MA systems, especially the dopaminergic, is associated with increased peripheral thyroid hormone activity.

KW - Dopamine

KW - serotonin

KW - thyroxine

KW - triiodothyroxine

U2 - 10.1007/s00702-003-0073-z

DO - 10.1007/s00702-003-0073-z

M3 - Article

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JO - Journal of Neural Transmission

JF - Journal of Neural Transmission

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ER -

The activity in the CNS catecholaminergic systems covaries with thyroid hormone metabolism in humans

Abstract

Subject classification (UKÄ)

Free keywords

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