TY - JOUR
T1 - The Benefits and Harms of Botulinum Toxin-A in the Treatment of Chronic Pelvic Pain Syndromes
T2 - A Systematic Review by the European Association of Urology Chronic Pelvic Pain Panel
AU - Parsons, Brian A.
AU - Goonewardene, Sanchia
AU - Dabestani, Saeed
AU - Pacheco-Figueiredo, Luis
AU - Yuan, Yuhong
AU - Zumstein, Valentin
AU - Cottrell, Angela M.
AU - Borovicka, Jan
AU - Dinis-Oliveira, Paulo
AU - Berghmans, Bary
AU - Elneil, Sohier
AU - Hughes, John
AU - Messelink, Bert E.J.
AU - de C Williams, Amanda C.
AU - Baranowski, Andrew P.
AU - Engeler, Daniel S.
PY - 2022
Y1 - 2022
N2 - Chronic pelvic pain (CPP) is chronic or persistent pain perceived in structures related to the pelvis of men and women. Patients with CPP may have pain refractory to conventional management strategies. Botulinum toxin A (BTX-A) injection is a potential therapeutic option in patients with CPP. Beneficial effects of BTX-A on pain, quality of life, and functional symptoms were seen in patients with certain CPP subtypes, but the current evidence level is too weak to allow recommendations about the use of BTX-A for treating CPP. Therefore, larger-scale, multicentre, well-designed, and appropriately powered randomised controlled trials or prospective case-control studies with longer follow-up periods are needed.
AB - Chronic pelvic pain (CPP) is chronic or persistent pain perceived in structures related to the pelvis of men and women. Patients with CPP may have pain refractory to conventional management strategies. Botulinum toxin A (BTX-A) injection is a potential therapeutic option in patients with CPP. Beneficial effects of BTX-A on pain, quality of life, and functional symptoms were seen in patients with certain CPP subtypes, but the current evidence level is too weak to allow recommendations about the use of BTX-A for treating CPP. Therefore, larger-scale, multicentre, well-designed, and appropriately powered randomised controlled trials or prospective case-control studies with longer follow-up periods are needed.
KW - Bladder pain syndrome
KW - Botulinum toxin A
KW - Chronic anal fissure
KW - Chronic pelvic pain syndrome
KW - Gynaecological pain syndrome
KW - Myofascial pelvic pain
KW - Prostate pain syndrome
U2 - 10.1016/j.euf.2021.01.005
DO - 10.1016/j.euf.2021.01.005
M3 - Review article
C2 - 33526405
AN - SCOPUS:85100174109
SN - 2405-4569
VL - 8
SP - 320
EP - 338
JO - European Urology Focus
JF - European Urology Focus
IS - 1
ER -