The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography

Magnus Dustler; Daniel Förnvik; Pontus Timberg; Hannie Petersson; Anders Tingberg; Sophia Zackrisson

doi:10.1007/978-3-319-41546-8_36

The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography

Magnus Dustler, Daniel Förnvik, Pontus Timberg, Hannie Petersson, Anders Tingberg, Sophia Zackrisson

Medical Radiation Physics, Malmö

Skåne University Hospital

Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

Abstract

Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.

Original language	English
Title of host publication	Breast Imaging
Subtitle of host publication	13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings
Editors	Anders Tingberg, Kristina Lång, Pontus Timberg
Publisher	Springer
Pages	282-288
Number of pages	7
Volume	9699
ISBN (Electronic)	978-3-319-41546-8
ISBN (Print)	9783319415451
DOIs	https://doi.org/10.1007/978-3-319-41546-8_36
Publication status	Published - 2016
Event	13th International Workshop on Breast Imaging, IWDM 2016 - Malmo, Sweden Duration: 2016 Jun 19 → 2016 Jun 22

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume	9699
ISSN (Print)	03029743
ISSN (Electronic)	16113349

Conference

Conference	13th International Workshop on Breast Imaging, IWDM 2016
Country/Territory	Sweden
City	Malmo
Period	2016/06/19 → 2016/06/22

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Subject classification (UKÄ)

Radiology and Medical Imaging

Free keywords

Elastography
Mammography
Mechanical imaging
Screening

Access to Document

10.1007/978-3-319-41546-8_36

Cite this

Dustler, M., Förnvik, D., Timberg, P., Petersson, H., Tingberg, A., & Zackrisson, S. (2016). The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography. In A. Tingberg, K. Lång, & P. Timberg (Eds.), Breast Imaging: 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings (Vol. 9699, pp. 282-288). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9699). Springer. https://doi.org/10.1007/978-3-319-41546-8_36

Dustler, Magnus ; Förnvik, Daniel ; Timberg, Pontus et al. / The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography. Breast Imaging: 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings. editor / Anders Tingberg ; Kristina Lång ; Pontus Timberg. Vol. 9699 Springer, 2016. pp. 282-288 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).

@inproceedings{2267bf40208f4d188782dc370f5febc3,

title = "The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography",

abstract = "Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.",

keywords = "Elastography, Mammography, Mechanical imaging, Screening",

author = "Magnus Dustler and Daniel F{\"o}rnvik and Pontus Timberg and Hannie Petersson and Anders Tingberg and Sophia Zackrisson",

year = "2016",

doi = "10.1007/978-3-319-41546-8\_36",

language = "English",

isbn = "9783319415451",

volume = "9699",

series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",

publisher = "Springer",

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editor = "Tingberg, \{Anders \} and Kristina L{\aa}ng and Pontus Timberg",

booktitle = "Breast Imaging",

address = "Germany",

note = "13th International Workshop on Breast Imaging, IWDM 2016 ; Conference date: 19-06-2016 Through 22-06-2016",

}

Dustler, M , Förnvik, D, Timberg, P, Petersson, H , Tingberg, A & Zackrisson, S 2016, The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography. in A Tingberg, K Lång & P Timberg (eds), Breast Imaging: 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings. vol. 9699, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 9699, Springer, pp. 282-288, 13th International Workshop on Breast Imaging, IWDM 2016, Malmo, Sweden, 2016/06/19. https://doi.org/10.1007/978-3-319-41546-8_36

The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography. / Dustler, Magnus ; Förnvik, Daniel; Timberg, Pontus et al.
Breast Imaging: 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings. ed. / Anders Tingberg; Kristina Lång; Pontus Timberg. Vol. 9699 Springer, 2016. p. 282-288 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 9699).

Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

TY - GEN

T1 - The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography

AU - Dustler, Magnus

AU - Förnvik, Daniel

AU - Timberg, Pontus

AU - Petersson, Hannie

AU - Tingberg, Anders

AU - Zackrisson, Sophia

PY - 2016

Y1 - 2016

N2 - Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.

AB - Breast cancer is diagnosed by a combination of modalities. Measuring the elasto-mechanical properties of suspicious lesions, by e.g. ultrasound elastography, can help differentiate malignant from benign findings. Using a prototype Mechanical Imaging (MI) system as an adjunct to mammography, the aim of this study was to characterize tumors using MI and compare the readings to those from the contralateral breast. Thirteen bilateral MI sets from women with malignant breast lesions were included in this study, drawn from a larger set of 155 women recalled from screening. The results showed that mean lesion pressure was significantly greater than the mean pressure of the corresponding breast, 7.5 ± 7.0 kPa compared to 2.5 ± 1.6 kPa (P = 0.01). There was no evidence for a difference in mean pressure or standard deviation of the MI image between symptomatic and contralateral asymptomatic breasts (P = 0.24 and 0.68). The results support that it is possible to use MI to distinguish malignant cancers from normal breast tissue. Still, further investigations of the characteristics of benign lesions are necessary to ascertain the usefulness of the system.

KW - Elastography

KW - Mammography

KW - Mechanical imaging

KW - Screening

UR - https://www.scopus.com/pages/publications/84977553497

U2 - 10.1007/978-3-319-41546-8_36

DO - 10.1007/978-3-319-41546-8_36

M3 - Paper in conference proceeding

AN - SCOPUS:84977553497

SN - 9783319415451

VL - 9699

T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

SP - 282

EP - 288

BT - Breast Imaging

A2 - Tingberg, Anders

A2 - Lång, Kristina

A2 - Timberg, Pontus

PB - Springer

T2 - 13th International Workshop on Breast Imaging, IWDM 2016

Y2 - 19 June 2016 through 22 June 2016

ER -

Dustler M , Förnvik D, Timberg P, Petersson H , Tingberg A , Zackrisson S. The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography. In Tingberg A, Lång K, Timberg P, editors, Breast Imaging: 13th International Workshop, IWDM 2016, Malmö, Sweden, June 19-22, 2016, Proceedings. Vol. 9699. Springer. 2016. p. 282-288. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)). doi: 10.1007/978-3-319-41546-8_36

The characteristics of malignant breast tumors imaged using a prototype mechanical imaging system as an adjunct to mammography

Abstract

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UN SDGs

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Free keywords

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