The diagnosis of bacteriuria during pregnancy

Siri Lorentzon, Birgitta Hovelius, Håkan Miörner, Maria Tendler, Anders E Åberg

Research output: Contribution to journalArticlepeer-review

Abstract

Three diagnostic tests, Nitur, Urobact, and Uricult, were evaluated in the detection of bacteriuria in 865 pregnant women. As reference method agar culture was performed. Heavy growth (greater than 10(5) CFU/ml) of urinary tract bacteria was considered a true positive result and demonstrated in 58 (6.7%) of the women, 14 of whom had gram-negative rods. The sensitivity of the nitrite test was extremely low (0.13). The test gave negative results in eight of 17 specimens yielding heavy growth of Escherichia coli or Proteus mirabilis. Although the Urobact test was highly sensitive as regards gram-negative infection, it had an unacceptably low (0.27) predictive value in positive tests. The sensitivity of the Uricult test was low (0.35) in this study. The predictive value (0.50) of a positive test result may be acceptable, since just over half of the false positive results were explainable by moderate growth of urinary tract pathogens (10(4)-10(5) CFU/ml). It is argued that semi-quantitative urine culture may be preferable to the rapid diagnostic methods studied for the screening of bacteriuria in pregnant women.
Original languageEnglish
Pages (from-to)81-83
JournalScandinavian Journal of Primary Health Care
Volume8
Issue number2
DOIs
Publication statusPublished - 1990

Subject classification (UKÄ)

  • Health Care Service and Management, Health Policy and Services and Health Economy

Keywords

  • kit
  • bacteriuria
  • pregnancy
  • screening

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