TY - JOUR
T1 - The effect of total body microwave hyperthermia and hepatic artery ligation on liver tumors—an experimental study in rats
AU - Carlsson, Goran
AU - Hafström, Larsolof
AU - Hugander, Anders
AU - Jönsson, Per‐Ebbe ‐E
AU - Bolmsjö, Magnus
AU - Persson, Bertil
PY - 1983/1/1
Y1 - 1983/1/1
N2 - The effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1 day after HAL, there was a 50% mortality.
AB - The effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1 day after HAL, there was a 50% mortality.
KW - hepatic artery ligation
KW - hyperthermia
KW - liver tumor
KW - microwaves
UR - http://www.scopus.com/inward/record.url?scp=0020658114&partnerID=8YFLogxK
U2 - 10.1002/jso.2930220110
DO - 10.1002/jso.2930220110
M3 - Article
C2 - 6823115
AN - SCOPUS:0020658114
SN - 0022-4790
VL - 22
SP - 37
EP - 40
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 1
ER -