The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

N.-O. Lindberg; E. Hansson; Björn Holmquist

doi:10.3109/03639048709068371

The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

N.-O. Lindberg, E. Hansson, Björn Holmquist

Department of Statistics

Research output: Contribution to journal › Article › peer-review

Abstract

Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.

Original language	English
Pages (from-to)	1069-1079
Journal	Drug Development and Industrial Pharmacy
Volume	13
Issue number	6
DOIs	https://doi.org/10.3109/03639048709068371
Publication status	Published - 1987

Subject classification (UKÄ)

Probability Theory and Statistics

Access to Document

10.3109/03639048709068371

Cite this

@article{08124751f31c4e8dbb7db730d7249c09,

title = "The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation",

abstract = "Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.",

author = "N.-O. Lindberg and E. Hansson and Bj{\"o}rn Holmquist",

year = "1987",

doi = "10.3109/03639048709068371",

language = "English",

volume = "13",

pages = "1069--1079",

journal = "Drug Development and Industrial Pharmacy",

issn = "0363-9045",

publisher = "Taylor & Francis",

number = "6",

}

TY - JOUR

T1 - The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

AU - Lindberg, N.-O.

AU - Hansson, E.

AU - Holmquist, Björn

PY - 1987

Y1 - 1987

N2 - Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.

AB - Intragranular porosity and liquid saturation were influenced by the impeller speed, the loss-on-drying of starch, the added amount of water and the drug concentration. A reduction of the impeller speed and the drug concentration decreased the porosity and increased the liquid saturation. Response surface contours were plotted.

U2 - 10.3109/03639048709068371

DO - 10.3109/03639048709068371

M3 - Article

SN - 0363-9045

VL - 13

SP - 1069

EP - 1079

JO - Drug Development and Industrial Pharmacy

JF - Drug Development and Industrial Pharmacy

IS - 6

ER -

The granulation of a tablet formulation in a high-speed mixer, Diosna P25. Influence on intra-granular porosity and liquid saturation

Abstract

Subject classification (UKÄ)

Access to Document

Fingerprint

Cite this