The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

Helena Fritz; David Lindgren; Börje Ljungberg; Håkan Axelson; Björn Dahlbäck

doi:10.1016/j.ejca.2014.03.281

The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

Helena Fritz, David Lindgren, Börje Ljungberg, Håkan Axelson, Björn Dahlbäck

Research output: Contribution to journal › Article › peer-review

229 Downloads (Pure)

Abstract

Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.

Original language	English
Pages (from-to)	1758-1765
Journal	European Journal of Cancer
Volume	50
Issue number	10
DOIs	https://doi.org/10.1016/j.ejca.2014.03.281
Publication status	Published - 2014

Subject classification (UKÄ)

Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.ejca.2014.03.281

Elsevier_Fritz_et_al

http://www.ncbi.nlm.nih.gov/pubmed/24793999?dopt=Abstract

1 Doctoral Thesis (compilation)

Axl RTK and microRNAs in urogenital cancers
Fritz, H., 2015, Translational Medicine. 218 p.
Research output: Thesis › Doctoral Thesis (compilation)

File

Cite this

@article{dfe6ee6d505f429e80f131527479e2f4,

title = "The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.",

abstract = "Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.",

author = "Helena Fritz and David Lindgren and B{\"o}rje Ljungberg and H{\aa}kan Axelson and Bj{\"o}rn Dahlb{\"a}ck",

year = "2014",

doi = "10.1016/j.ejca.2014.03.281",

language = "English",

volume = "50",

pages = "1758--1765",

journal = "European Journal of Cancer",

issn = "1879-0852",

publisher = "Elsevier",

number = "10",

}

TY - JOUR

T1 - The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

AU - Fritz, Helena

AU - Lindgren, David

AU - Ljungberg, Börje

AU - Axelson, Håkan

AU - Dahlbäck, Björn

PY - 2014

Y1 - 2014

N2 - Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.

AB - Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.

U2 - 10.1016/j.ejca.2014.03.281

DO - 10.1016/j.ejca.2014.03.281

M3 - Article

C2 - 24793999

SN - 1879-0852

VL - 50

SP - 1758

EP - 1765

JO - European Journal of Cancer

JF - European Journal of Cancer

IS - 10

ER -

The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

Abstract

Subject classification (UKÄ)

UN SDGs

Access to Document

Fingerprint

Research output

Axl RTK and microRNAs in urogenital cancers

Cite this