The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.

Lao Saal; Johan Vallon-Christersson; Jari Häkkinen; Cecilia Hegardt; Dorthe Grabau; Christof Winter; Christian Brueffer; Man-Hung Eric Tang; Christel Reuterswärd; Ralph Schulz; Anna K Karlsson; Anna Ehinger; Janne Malina; Jonas Manjer; Martin Malmberg; Christer Larsson; Lisa Rydén; Niklas Loman; Åke Borg

doi:10.1186/s13073-015-0131-9

The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.

Lao Saal, Johan Vallon-Christersson, Jari Häkkinen, Cecilia Hegardt, Dorthe Grabau, Christof Winter, Christian Brueffer, Man-Hung Eric Tang, Christel Reuterswärd, Ralph Schulz, Anna K Karlsson, Anna Ehinger, Janne Malina, Jonas Manjer, Martin Malmberg, Christer Larsson, Lisa Rydén, Niklas Loman, Åke Borg

Skåne University Hospital

Research output: Contribution to journal › Article › peer-review

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Abstract

Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.

Original language	English
Article number	20
Journal	Genome Medicine
Volume	7
Issue number	1
DOIs	https://doi.org/10.1186/s13073-015-0131-9
Publication status	Published - 2015

Subject classification (UKÄ)

Surgery
Cancer and Oncology

Access to Document

10.1186/s13073-015-0131-9

BMC__Saal_et_al

http://www.ncbi.nlm.nih.gov/pubmed/25722745?dopt=Abstract

1 Doctoral Thesis (compilation)

RNA Sequencing for Molecular Diagnostics in Breast Cancer
Brueffer, C., 2021, Lund: Lund University, Faculty of Medicine. 110 p.
Research output: Thesis › Doctoral Thesis (compilation)

Open Access
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2 Active

Sweden Cancerome Analysis Network - Breast (SCAN-B): a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine
Borg, Å., Ehinger, A., Hegardt, C., Larsson, C., Loman, N., Malmberg, M., Ryden, L. & Saal, L.
2009/06/01 → …
Project: Network
Breast Cancer Surgery
Ryden, L., Malmström, M. & Niméus, E.
2000/01/03 → …
Project: Research
RNA sequencing for molecular diagnostics in breast cancer
Brueffer, C., Saal, L., Höglund, M. & Axelson, H.
2014/06/01 → 2021/01/13
Project: Dissertation

1 Member of board/committee/council etc

Sweden Cancerome Analysis Network – Breast (SCAN-B)
Anna Ehinger (Contributor)
2010 → …
Activity: Consultancy, expert advice and memberships › Member of board/committee/council etc

Cite this

Saal, L., Vallon-Christersson, J., Häkkinen, J., Hegardt, C., Grabau, D., Winter, C., Brueffer, C., Tang, M-H. E., Reuterswärd, C., Schulz, R., Karlsson, A. K., Ehinger, A., Malina, J., Manjer, J., Malmberg, M., Larsson, C., Rydén, L., Loman, N., & Borg, Å. (2015). The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine. Genome Medicine, 7(1), [20]. https://doi.org/10.1186/s13073-015-0131-9

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title = "The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.",

abstract = "Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.",

author = "Lao Saal and Johan Vallon-Christersson and Jari H{\"a}kkinen and Cecilia Hegardt and Dorthe Grabau and Christof Winter and Christian Brueffer and Tang, {Man-Hung Eric} and Christel Reutersw{\"a}rd and Ralph Schulz and Karlsson, {Anna K} and Anna Ehinger and Janne Malina and Jonas Manjer and Martin Malmberg and Christer Larsson and Lisa Ryd{\'e}n and Niklas Loman and {\AA}ke Borg",

year = "2015",

doi = "10.1186/s13073-015-0131-9",

language = "English",

volume = "7",

journal = "Genome Medicine",

issn = "1756-994X",

publisher = "BioMed Central (BMC)",

number = "1",

}

Saal, L , Vallon-Christersson, J , Häkkinen, J , Hegardt, C, Grabau, D, Winter, C, Brueffer, C, Tang, M-HE, Reuterswärd, C, Schulz, R, Karlsson, AK, Ehinger, A, Malina, J, Manjer, J, Malmberg, M, Larsson, C , Rydén, L , Loman, N & Borg, Å 2015, 'The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.', Genome Medicine, vol. 7, no. 1, 20. https://doi.org/10.1186/s13073-015-0131-9

TY - JOUR

T1 - The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.

AU - Saal, Lao

AU - Vallon-Christersson, Johan

AU - Häkkinen, Jari

AU - Hegardt, Cecilia

AU - Grabau, Dorthe

AU - Winter, Christof

AU - Brueffer, Christian

AU - Tang, Man-Hung Eric

AU - Reuterswärd, Christel

AU - Schulz, Ralph

AU - Karlsson, Anna K

AU - Ehinger, Anna

AU - Malina, Janne

AU - Manjer, Jonas

AU - Malmberg, Martin

AU - Larsson, Christer

AU - Rydén, Lisa

AU - Loman, Niklas

AU - Borg, Åke

PY - 2015

Y1 - 2015

N2 - Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.

AB - Breast cancer exhibits significant molecular, pathological, and clinical heterogeneity. Current clinicopathological evaluation is imperfect for predicting outcome, which results in overtreatment for many patients, and for others, leads to death from recurrent disease. Therefore, additional criteria are needed to better personalize care and maximize treatment effectiveness and survival.

U2 - 10.1186/s13073-015-0131-9

DO - 10.1186/s13073-015-0131-9

M3 - Article

C2 - 25722745

SN - 1756-994X

VL - 7

JO - Genome Medicine

JF - Genome Medicine

IS - 1

M1 - 20

ER -

The Sweden Cancerome Analysis Network - Breast (SCAN-B) Initiative: a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine.

Abstract

Subject classification (UKÄ)

Access to Document

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Research output

RNA Sequencing for Molecular Diagnostics in Breast Cancer

Projects

Sweden Cancerome Analysis Network - Breast (SCAN-B): a large-scale multicenter infrastructure towards implementation of breast cancer genomic analyses in the clinical routine

Breast Cancer Surgery

RNA sequencing for molecular diagnostics in breast cancer

Activities

Sweden Cancerome Analysis Network – Breast (SCAN-B)

Cite this