The use of analgesics and hypnotics in relation to self-rated health and disability pension - A prospective study of middle-aged men

Aims: This cohort study on urban middle-aged men investigates the association between the use of analgesics and hypnotics, self-rated health (SRI-I) and disability pension. Methods: Five birth-year cohorts of middle-aged, urban, Swedish men were invited to a screening programme and were followed for approximately 11 years. Results: Out of all the subjects (n = 5798), 12.4% received a disability pension during follow-up, 27.0% rated their health as less than perfect, 10.6% used analgesics and 2.9% used hypnotics. Compared with non-users of analgesics and hypnotics, the adjusted hazard ratio of disability pension for the simultaneous use of both drugs was 7.0 (95% CI: 4.3, 11.6) and the adjusted odds ratio of poor SRH was 16.5 (6.3, 43.5). Thus, the use of analgesics and hypnotics was positively related to poor SRH and predicted award of a disability pension within an Ii-year follow-up. This may reflect that the use of analgesics and hypnotics is a proxy of disease but an independent negative effect on health cannot be excluded. Conclusions: Information on the use of these drugs could be used to predict the award of a disability pension, such as in different geographical areas or population groups.