The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

Francesca Forzano; Olga Antonova; Angus Clarke; Guido de Wert; Sabine Hentze; Yalda Jamshidi; Yves Moreau; Markus Perola; Inga Prokopenko; Andrew Read; Alexandre Reymond; Vigdis Stefansdottir; Carla van El; Maurizio Genuardi; Borut Peterlin; Carla Oliveira; Karin Writzl; Gunnar Douzgos Houge; Christophe Cordier; Heidi Howard; Milan Macek; Béla Melegh; Alvaro Mendes; Dragica Radojkovic; Emmanuelle Rial-Sebbag; Fiona Ulph; on behalf of the Executive Committee of the European Society of Human Genetics; Public and Professional Policy Committee of the European Society of Human Genetics

doi:10.1038/s41431-021-01000-x

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

Francesca Forzano, Olga Antonova, Angus Clarke, Guido de Wert, Sabine Hentze, Yalda Jamshidi, Yves Moreau, Markus Perola, Inga Prokopenko, Andrew Read, Alexandre Reymond, Vigdis Stefansdottir, Carla van El, Maurizio Genuardi, Borut Peterlin, Carla Oliveira, Karin Writzl, Gunnar Douzgos Houge, Christophe Cordier, Heidi HowardMilan Macek, Béla Melegh, Alvaro Mendes, Dragica Radojkovic, Emmanuelle Rial-Sebbag, Fiona Ulph, on behalf of the Executive Committee of the European Society of Human Genetics, Public and Professional Policy Committee of the European Society of Human Genetics

Medical Ethics

Research output: Contribution to journal › Article › peer-review

Original language	English
Pages (from-to)	493-495
Number of pages	3
Journal	European Journal of Human Genetics
Volume	30
Issue number	5
DOIs	https://doi.org/10.1038/s41431-021-01000-x
Publication status	Published - 2022 May

Subject classification (UKÄ)

Medical Ethics
Medical Genetics and Genomics (including Gene Therapy)

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Forzano, F., Antonova, O., Clarke, A., de Wert, G., Hentze, S., Jamshidi, Y., Moreau, Y., Perola, M., Prokopenko, I., Read, A., Reymond, A., Stefansdottir, V., van El, C., Genuardi, M., Peterlin, B., Oliveira, C., Writzl, K., Houge, G. D., Cordier, C., ... Public and Professional Policy Committee of the European Society of Human Genetics (2022). The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice. European Journal of Human Genetics, 30(5), 493-495. https://doi.org/10.1038/s41431-021-01000-x

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title = "The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice",

author = "Francesca Forzano and Olga Antonova and Angus Clarke and {de Wert}, Guido and Sabine Hentze and Yalda Jamshidi and Yves Moreau and Markus Perola and Inga Prokopenko and Andrew Read and Alexandre Reymond and Vigdis Stefansdottir and {van El}, Carla and Maurizio Genuardi and Borut Peterlin and Carla Oliveira and Karin Writzl and Houge, {Gunnar Douzgos} and Christophe Cordier and Heidi Howard and Milan Macek and B{\'e}la Melegh and Alvaro Mendes and Dragica Radojkovic and Emmanuelle Rial-Sebbag and Fiona Ulph and {on behalf of the Executive Committee of the European Society of Human Genetics} and {Public and Professional Policy Committee of the European Society of Human Genetics}",

year = "2022",

month = may,

doi = "10.1038/s41431-021-01000-x",

language = "English",

volume = "30",

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Forzano, F, Antonova, O, Clarke, A, de Wert, G, Hentze, S, Jamshidi, Y, Moreau, Y, Perola, M, Prokopenko, I, Read, A, Reymond, A, Stefansdottir, V, van El, C, Genuardi, M, Peterlin, B, Oliveira, C, Writzl, K, Houge, GD, Cordier, C, Howard, H, Macek, M, Melegh, B, Mendes, A, Radojkovic, D, Rial-Sebbag, E, Ulph, F, on behalf of the Executive Committee of the European Society of Human Genetics & Public and Professional Policy Committee of the European Society of Human Genetics 2022, 'The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice', European Journal of Human Genetics, vol. 30, no. 5, pp. 493-495. https://doi.org/10.1038/s41431-021-01000-x

TY - JOUR

T1 - The use of polygenic risk scores in pre-implantation genetic testing

T2 - an unproven, unethical practice

AU - Forzano, Francesca

AU - Antonova, Olga

AU - Clarke, Angus

AU - de Wert, Guido

AU - Hentze, Sabine

AU - Jamshidi, Yalda

AU - Moreau, Yves

AU - Perola, Markus

AU - Prokopenko, Inga

AU - Read, Andrew

AU - Reymond, Alexandre

AU - Stefansdottir, Vigdis

AU - van El, Carla

AU - Genuardi, Maurizio

AU - Peterlin, Borut

AU - Oliveira, Carla

AU - Writzl, Karin

AU - Houge, Gunnar Douzgos

AU - Cordier, Christophe

AU - Howard, Heidi

AU - Macek, Milan

AU - Melegh, Béla

AU - Mendes, Alvaro

AU - Radojkovic, Dragica

AU - Rial-Sebbag, Emmanuelle

AU - Ulph, Fiona

AU - on behalf of the Executive Committee of the European Society of Human Genetics

AU - Public and Professional Policy Committee of the European Society of Human Genetics

PY - 2022/5

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ER -

The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice

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