Thrombotic occlusion of all left coronary branches in a young woman with severe ulcerative colitis

Carl Gunnar Gustavsson, Peter Svensson, Erik Hertervig, Sandhall Lennart, Hårdhammar Peter, Malcevschi-Lind Natascia, Sven-Erik Olsson

Research output: Contribution to journalLetterpeer-review

Abstract

Background. The thrombosis risk is increased in active ulcerative colitis. The limited number of reported complications have
predominantly been cerebrovascular but other vessel territories may also be affected. Patient. During a severe attack of ulcerative
colitis a 37-year-old woman suffered occlusion of all left coronary artery branches. Serial angiographies showed progressive
recanalisation of the coronary arteries during anticoagulation, but no atherosclerotic stenosis. The cause of infarction was thus
considered to be an extensive coronary thrombosis. However, a large battery of blood tests failed to identify any procoagulant
abnormality. Conclusion. Evidence is now accumulating that the increased thrombosis risk also may involve the coronary arteries,
even in young patients. To the best of our knowledge this is the third reported case ofmyocardial infarction despite angiographically
normal coronary arteries in a patient with active ulcerative colitis. The extent of affected myocardiumwas in this case exceptionally
large.
Original languageEnglish
Article number134631
JournalISRN Cardiology
DOIs
Publication statusPublished - 2011

Subject classification (UKÄ)

  • Public Health, Global Health, Social Medicine and Epidemiology

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