Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.

Bodil Gesslein; Gisela Håkansson; Lotta Gustafsson; Per Ekström; Malin Malmsjö

Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.

Bodil Gesslein, Gisela Håkansson, Lotta Gustafsson, Per Ekström, Malin Malmsjö

Research output: Contribution to journal › Article › peer-review

Abstract

Numerous studies have been performed aimed at limiting the extent of retinal injury after ischemia, but there is still no effective pharmacological treatment available. The aim of the present study was to examine the role of tumor necrosis factor (TNF)α and its receptors (TNF-R1 and TNF-R2), especially considering the neuroretina and the retinal vasculature since the retinal blood vessels are key organs in circulatory failure.

Original language	English
Pages (from-to)	2317-2327
Journal	Molecular Vision
Volume	16
Publication status	Published - 2010

Subject classification (UKÄ)

Biological Sciences

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title = "Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.",

abstract = "Numerous studies have been performed aimed at limiting the extent of retinal injury after ischemia, but there is still no effective pharmacological treatment available. The aim of the present study was to examine the role of tumor necrosis factor (TNF)α and its receptors (TNF-R1 and TNF-R2), especially considering the neuroretina and the retinal vasculature since the retinal blood vessels are key organs in circulatory failure.",

author = "Bodil Gesslein and Gisela H{\aa}kansson and Lotta Gustafsson and Per Ekstr{\"o}m and Malin Malmsj{\"o}",

year = "2010",

language = "English",

volume = "16",

pages = "2317--2327",

journal = "Molecular Vision",

issn = "1090-0535",

publisher = "Molecular Vision",

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TY - JOUR

T1 - Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.

AU - Gesslein, Bodil

AU - Håkansson, Gisela

AU - Gustafsson, Lotta

AU - Ekström, Per

AU - Malmsjö, Malin

PY - 2010

Y1 - 2010

N2 - Numerous studies have been performed aimed at limiting the extent of retinal injury after ischemia, but there is still no effective pharmacological treatment available. The aim of the present study was to examine the role of tumor necrosis factor (TNF)α and its receptors (TNF-R1 and TNF-R2), especially considering the neuroretina and the retinal vasculature since the retinal blood vessels are key organs in circulatory failure.

AB - Numerous studies have been performed aimed at limiting the extent of retinal injury after ischemia, but there is still no effective pharmacological treatment available. The aim of the present study was to examine the role of tumor necrosis factor (TNF)α and its receptors (TNF-R1 and TNF-R2), especially considering the neuroretina and the retinal vasculature since the retinal blood vessels are key organs in circulatory failure.

M3 - Article

SN - 1090-0535

VL - 16

SP - 2317

EP - 2327

JO - Molecular Vision

JF - Molecular Vision

ER -

Tumor necrosis factor and its receptors in the neuroretina and retinal vasculature after ischemia-reperfusion injury in the pig retina.

Abstract

Subject classification (UKÄ)

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