Tumour Localization by Means of Laser-Induced Fluorescence in Hematoporphyrin Derivative (HPD) — Bearing Tissue

S. Andersson, Jaro Ankerst, Elisabeth Kjellén, S Montan, E Sjöholm, Katarina Svanberg, Sune Svanberg

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

Following systemic injection, hematoporphyrin derivative (HPD) is known to be selectively retained in malignant tissue. This property can be used in a two-fold way: a) for localizing tumours by observing the characteristic dual-peaked laser-induced fluorescence from HPD, and b) for photodynamic therapy (HPD-PDT) using a localized HPD-assisted singlet oxygen release induced by irradiation of 630 nm laser light. This rapidly developing field has recently been reviewed by DOUGHERTY.
Original languageEnglish
Title of host publicationLaser Spectroscopy VII
Subtitle of host publicationProceedings of the Seventh International Conference, Hawaii, June 24-28, 1985
PublisherSpringer
Pages401-406
ISBN (Electronic)978-3-540-39664-2
ISBN (Print)978-3-662-15253-9
DOIs
Publication statusPublished - 1985

Subject classification (UKÄ)

  • Atom and Molecular Physics and Optics
  • Cancer and Oncology

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