Twelve-Single Nucleotide Polymorphism Genetic Risk Score Identifies Individuals at Increased Risk for Future Atrial Fibrillation and Stroke.

Hayato Tada, Dov Shiffman, Gustav Smith, Marketa Sjögren, Steven A Lubitz, Patrick T Ellinor, Judy Z Louie, Joseph J Catanese, Gunnar Engström, James J Devlin, Sekar Kathiresan, Olle Melander

Research output: Contribution to journalArticlepeer-review

65 Citations (SciVal)

Abstract

Atrial fibrillation (AF) is prevalent and there is a clinical need for biomarkers to identify individuals at higher risk for AF. Fixed throughout a life course and assayable early in life, genetic biomarkers may meet this need. Here, we investigate whether multiple single nucleotide polymorphisms together as an AF genetic risk score (AF-GRS) can improve prediction of one's risk for AF.
Original languageEnglish
Pages (from-to)2856
Journal Stroke: a journal of cerebral circulation
Volume45
Issue number10
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Neurology

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