Research output per year
Research output per year
Jens Prothmann, Mingzhe Sun, Peter Spégel, Margareta Sandahl, Charlotta Turner
Research output: Contribution to journal › Article › peer-review
The conversion of lignin to potentially high-value low molecular weight compounds often results in complex mixtures of monomeric and oligomeric compounds. In this study, a method for the quantitative and qualitative analysis of 40 lignin-derived compounds using ultra-high-performance supercritical fluid chromatography coupled to quadrupole-time-of-flight mass spectrometry (UHPSFC/QTOF-MS) has been developed. Seven different columns were explored for maximum selectivity. Makeup solvent composition and ion source settings were optimised using a D-optimal design of experiment (DoE). Differently processed lignin samples were analysed and used for the method validation. The new UHPSFC/QTOF-MS method showed good separation of the 40 compounds within only 6-min retention time, and out of these, 36 showed high ionisation efficiency in negative electrospray ionisation mode. [Figure not available: see fulltext.]
Original language | English |
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Pages (from-to) | 7049-7061 |
Journal | Analytical and Bioanalytical Chemistry |
Volume | 409 |
Issue number | 30 |
Early online date | 2017 Oct 13 |
DOIs | |
Publication status | Published - 2017 Dec |
Research output: Thesis › Doctoral Thesis (compilation)
Research output: Thesis › Doctoral Thesis (compilation)