@inproceedings{2e8b93df22074bd18873fbbe9de5fa43,
title = "Using Bayesian neural networks with ARD input selection to detect malignant ovarian masses prior to surgery",
abstract = "In this paper, we applied Bayesian multi-layer perceptrons (MLP) using the evidence procedure to predict malignancy of ovarian masses in a large (n = 1,066) multi-centre data set. Automatic relevance determination (ARD) was used to select the most relevant inputs. Fivefold cross-validation (5CV) and repeated 5CV was used to select the optimal combination of input set and number of hidden neurons. Results indicate good performance of the models with area under the receiver operating characteristic curve values of 0.93-0.94 on independent data. Comparison with a linear benchmark model and a previously developed logistic regression model shows that the present problem is very well linearly separable. A resampling analysis further shows that the number of hidden neurons specified in the ARD analyses for input selection may influence model performance. This paper shows that Bayesian MLPs, although not frequently used, are a useful tool for detecting malignant ovarian tumours.",
keywords = "ultrasound, automatic relevance determination, netlab, evidence framework, Bayesian, ovarian tumour classification, multi-layer perceptrons",
author = "{Van Calster}, Ben and Dirk Timmerman and Nabney, {Ian T.} and Lil Valentin and Testa, {Antonia C.} and {Van Holsbeke}, Caroline and Ignace Vergote and {Van Huffel}, Sabine",
year = "2008",
doi = "10.1007/s00521-007-0147-1",
language = "English",
volume = "17",
publisher = "Springer",
number = "5-6",
pages = "489--500",
booktitle = "NEURAL COMPUTING & APPLICATIONS",
address = "Germany",
note = "28th Annual International Conference of the IEEE-Engineering-in-Medicine-and-Biology-Society ; Conference date: 30-08-2006 Through 03-09-2006",
}