Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

Dmitry Shungin; Marilyn C Cornelis; Kimon Divaris; Birte Holtfreter; John R Shaffer; Yau-Hua Yu; Silvana P Barros; James D Beck; Reiner Biffar; Eric A Boerwinkle; Richard J Crout; Andrea Ganna; Goran Hallmans; George Hindy; Frank B Hu; Peter Kraft; Daniel W McNeil; Olle Melander; Kevin L Moss; Kari E North; Marju Orho-Melander; Nancy L Pedersen; Paul M Ridker; Eric B Rimm; Lynda M Rose; Gull Rukh; Alexander Teumer; Robert J Weyant; Daniel I Chasman; Kaumudi Joshipura; Thomas Kocher; Patrik Ke Magnusson; Mary L Marazita; Peter Nilsson; Steve Offenbacher; George Davey Smith; Pernilla Lundberg; Tom M Palmer; Nicholas J Timpson; Ingegerd Johansson; Paul Franks

doi:10.1093/ije/dyv075

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

Dmitry Shungin, Marilyn C Cornelis, Kimon Divaris, Birte Holtfreter, John R Shaffer, Yau-Hua Yu, Silvana P Barros, James D Beck, Reiner Biffar, Eric A Boerwinkle, Richard J Crout, Andrea Ganna, Goran Hallmans, George Hindy, Frank B Hu, Peter Kraft, Daniel W McNeil, Olle Melander, Kevin L Moss, Kari E NorthMarju Orho-Melander, Nancy L Pedersen, Paul M Ridker, Eric B Rimm, Lynda M Rose, Gull Rukh, Alexander Teumer, Robert J Weyant, Daniel I Chasman, Kaumudi Joshipura, Thomas Kocher, Patrik Ke Magnusson, Mary L Marazita, Peter Nilsson, Steve Offenbacher, George Davey Smith, Pernilla Lundberg, Tom M Palmer, Nicholas J Timpson, Ingegerd Johansson, Paul Franks

Research output: Contribution to journal › Article › peer-review

Abstract

The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).

Original language	English
Pages (from-to)	638-650
Journal	International Journal of Epidemiology
Volume	44
Issue number	2
DOIs	https://doi.org/10.1093/ije/dyv075
Publication status	Published - 2015

Subject classification (UKÄ)

Health Sciences

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1093/ije/dyv075

http://www.ncbi.nlm.nih.gov/pubmed/26050256?dopt=Abstract

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Shungin, D., Cornelis, M. C., Divaris, K., Holtfreter, B., Shaffer, J. R., Yu, Y.-H., Barros, S. P., Beck, J. D., Biffar, R., Boerwinkle, E. A., Crout, R. J., Ganna, A., Hallmans, G., Hindy, G., Hu, F. B., Kraft, P., McNeil, D. W., Melander, O., Moss, K. L., ... Franks, P. (2015). Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium. International Journal of Epidemiology, 44(2), 638-650. https://doi.org/10.1093/ije/dyv075

@article{8d7b3307263c4f89bcc723da24d1949f,

title = "Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.",

abstract = "The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).",

author = "Dmitry Shungin and Cornelis, {Marilyn C} and Kimon Divaris and Birte Holtfreter and Shaffer, {John R} and Yau-Hua Yu and Barros, {Silvana P} and Beck, {James D} and Reiner Biffar and Boerwinkle, {Eric A} and Crout, {Richard J} and Andrea Ganna and Goran Hallmans and George Hindy and Hu, {Frank B} and Peter Kraft and McNeil, {Daniel W} and Olle Melander and Moss, {Kevin L} and North, {Kari E} and Marju Orho-Melander and Pedersen, {Nancy L} and Ridker, {Paul M} and Rimm, {Eric B} and Rose, {Lynda M} and Gull Rukh and Alexander Teumer and Weyant, {Robert J} and Chasman, {Daniel I} and Kaumudi Joshipura and Thomas Kocher and Magnusson, {Patrik Ke} and Marazita, {Mary L} and Peter Nilsson and Steve Offenbacher and {Davey Smith}, George and Pernilla Lundberg and Palmer, {Tom M} and Timpson, {Nicholas J} and Ingegerd Johansson and Paul Franks",

year = "2015",

doi = "10.1093/ije/dyv075",

language = "English",

volume = "44",

pages = "638--650",

journal = "International Journal of Epidemiology",

issn = "1464-3685",

publisher = "Oxford University Press",

number = "2",

}

Shungin, D, Cornelis, MC, Divaris, K, Holtfreter, B, Shaffer, JR, Yu, Y-H, Barros, SP, Beck, JD, Biffar, R, Boerwinkle, EA, Crout, RJ, Ganna, A, Hallmans, G, Hindy, G, Hu, FB, Kraft, P, McNeil, DW, Melander, O, Moss, KL, North, KE, Orho-Melander, M, Pedersen, NL, Ridker, PM, Rimm, EB, Rose, LM, Rukh, G, Teumer, A, Weyant, RJ, Chasman, DI, Joshipura, K, Kocher, T, Magnusson, PK, Marazita, ML, Nilsson, P, Offenbacher, S, Davey Smith, G, Lundberg, P, Palmer, TM, Timpson, NJ, Johansson, I & Franks, P 2015, 'Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.', International Journal of Epidemiology, vol. 44, no. 2, pp. 638-650. https://doi.org/10.1093/ije/dyv075

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium. / Shungin, Dmitry; Cornelis, Marilyn C; Divaris, Kimon et al.
In: International Journal of Epidemiology, Vol. 44, No. 2, 2015, p. 638-650.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

AU - Shungin, Dmitry

AU - Cornelis, Marilyn C

AU - Divaris, Kimon

AU - Holtfreter, Birte

AU - Shaffer, John R

AU - Yu, Yau-Hua

AU - Barros, Silvana P

AU - Beck, James D

AU - Biffar, Reiner

AU - Boerwinkle, Eric A

AU - Crout, Richard J

AU - Ganna, Andrea

AU - Hallmans, Goran

AU - Hindy, George

AU - Hu, Frank B

AU - Kraft, Peter

AU - McNeil, Daniel W

AU - Melander, Olle

AU - Moss, Kevin L

AU - North, Kari E

AU - Orho-Melander, Marju

AU - Pedersen, Nancy L

AU - Ridker, Paul M

AU - Rimm, Eric B

AU - Rose, Lynda M

AU - Rukh, Gull

AU - Teumer, Alexander

AU - Weyant, Robert J

AU - Chasman, Daniel I

AU - Joshipura, Kaumudi

AU - Kocher, Thomas

AU - Magnusson, Patrik Ke

AU - Marazita, Mary L

AU - Nilsson, Peter

AU - Offenbacher, Steve

AU - Davey Smith, George

AU - Lundberg, Pernilla

AU - Palmer, Tom M

AU - Timpson, Nicholas J

AU - Johansson, Ingegerd

AU - Franks, Paul

PY - 2015

Y1 - 2015

N2 - The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).

AB - The observational relationship between obesity and periodontitis is widely known, yet causal evidence is lacking. Our objective was to investigate causal associations between periodontitis and body mass index (BMI).

U2 - 10.1093/ije/dyv075

DO - 10.1093/ije/dyv075

M3 - Article

C2 - 26050256

SN - 1464-3685

VL - 44

SP - 638

EP - 650

JO - International Journal of Epidemiology

JF - International Journal of Epidemiology

IS - 2

ER -

Using genetics to test the causal relationship of total adiposity and periodontitis: Mendelian randomization analyses in the Gene-Lifestyle Interactions and Dental Endpoints (GLIDE) Consortium.

Abstract

Subject classification (UKÄ)

UN SDGs

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