Abstract
Nerve fibres displaying immunoreactivity for vasoactive intestinal polypeptide (VIP) were found in the wall of the portal vein in cats, guinea pigs, rats and mice. In whole-mount preparations a sparse network of VIP fibres was seen in the vessel wall. Electrical field stimulation of the rat portal vein in vitro caused a significant release of VIP. The results suggest that VIP ergic nerve fibres play a role in the regulation of portal blood flow.
Original language | English |
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Pages (from-to) | 617-624 |
Journal | Cell and Tissue Research |
Volume | 221 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1982 |
Subject classification (UKÄ)
- Cell Biology
Free keywords
- Vasoactive intestinal polypeptide (VIP)
- Peptidergic nerves
- Portalvein
- Vascular effects