Weight gain and blood pressure

Johan Sundström; Lars Lind; Erik Lampa; Oskar Angerås; Erasmus Bachus; Göran Bergström; Bo Carlberg; Gunnar Engström; Jan E Engvall; Mats Eriksson; Bruna Gigante; Emil Hagström; Ola Hjelmgren; Jan-Håkan Jansson; Tomas Jernberg; Maria Mannila; Fredrik H Nyström; Jonas Oldgren; Margaretha Persson; Anette Sandström; Eva Swahn; Stefan Söderberg; Kjell Torén; Carl Johan Östgren; Annika Rosengren

doi:10.1097/HJH.0000000000002298

Weight gain and blood pressure

Johan Sundström, Lars Lind, Erik Lampa, Oskar Angerås, Erasmus Bachus, Göran Bergström, Bo Carlberg, Gunnar Engström, Jan E Engvall, Mats Eriksson, Bruna Gigante, Emil Hagström, Ola Hjelmgren, Jan-Håkan Jansson, Tomas Jernberg, Maria Mannila, Fredrik H Nyström, Jonas Oldgren, Margaretha Persson, Anette SandströmEva Swahn, Stefan Söderberg, Kjell Torén, Carl Johan Östgren, Annika Rosengren

Research output: Contribution to journal › Article › peer-review

Abstract

OBJECTIVE: Although the causality of the obesity--hypertension association is established, the potential for prevention is not. We hypothesized that weight gain between early adulthood and mid-life is associated with higher mid-life blood pressure.

METHODS: We investigated the hypothesis using a large contemporaneous population-based mid-life cohort of men and women aged 50-64 years. Recalled body weight at age 20 years was self-reported, and mid-life body weight and office blood pressures were measured in accordance with a detailed protocol.

RESULTS: On average, men had gained 14.9 (95% CI 14.6-15.2) kg of weight, and women 14.6 (95% CI 14.4-14.9) kg, between age 20 years and the mid-life examination, corresponding to 0.40 (95% CI 0.39-0.41) kg/year for men and women. Both weight at age 20 years and weight at the mid-life examination were associated with mid-life blood pressures. On average, a 10 kg weight increase between age 20 years and mid-life was associated with 2.2 (95% CI 0.9-3.5) mmHg higher systolic and 1.7 (95% CI 0.9-2.5) mmHg higher diastolic mid-life blood pressure in men, and 3.2 (2.5-4.0) mmHg higher systolic and 2.4 (1.9-2.9) mmHg higher diastolic mid-life blood pressure in women. Mid-life weight was more closely associated than weight at age 20 years with mid-life blood pressure. For a given mid-life weight, blood pressure was higher in persons with higher weight gain from age 20 years.

CONCLUSION: In sum, weight gain between early adulthood and mid-life was associated with higher mid-life blood pressure. The magnitude of the association indicates a potentially great public health impact of strategies to prevent weight gain throughout adulthood.

Original language	English
Pages (from-to)	387-394
Number of pages	8
Journal	Journal of Hypertension
Volume	38
Issue number	3
DOIs	https://doi.org/10.1097/HJH.0000000000002298
Publication status	Published - 2020 Mar

Subject classification (UKÄ)

Cardiac and Cardiovascular Systems

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/HJH.0000000000002298

Cite this

Sundström, J., Lind, L., Lampa, E., Angerås, O., Bachus, E., Bergström, G., Carlberg, B., Engström, G., Engvall, J. E., Eriksson, M., Gigante, B., Hagström, E., Hjelmgren, O., Jansson, J.-H., Jernberg, T., Mannila, M., Nyström, F. H., Oldgren, J., Persson, M., ... Rosengren, A. (2020). Weight gain and blood pressure. Journal of Hypertension, 38(3), 387-394. https://doi.org/10.1097/HJH.0000000000002298

@article{ba56f2344f4347d8a258376874ff203b,

title = "Weight gain and blood pressure",

abstract = "OBJECTIVE: Although the causality of the obesity--hypertension association is established, the potential for prevention is not. We hypothesized that weight gain between early adulthood and mid-life is associated with higher mid-life blood pressure.METHODS: We investigated the hypothesis using a large contemporaneous population-based mid-life cohort of men and women aged 50-64 years. Recalled body weight at age 20 years was self-reported, and mid-life body weight and office blood pressures were measured in accordance with a detailed protocol.RESULTS: On average, men had gained 14.9 (95% CI 14.6-15.2) kg of weight, and women 14.6 (95% CI 14.4-14.9) kg, between age 20 years and the mid-life examination, corresponding to 0.40 (95% CI 0.39-0.41) kg/year for men and women. Both weight at age 20 years and weight at the mid-life examination were associated with mid-life blood pressures. On average, a 10 kg weight increase between age 20 years and mid-life was associated with 2.2 (95% CI 0.9-3.5) mmHg higher systolic and 1.7 (95% CI 0.9-2.5) mmHg higher diastolic mid-life blood pressure in men, and 3.2 (2.5-4.0) mmHg higher systolic and 2.4 (1.9-2.9) mmHg higher diastolic mid-life blood pressure in women. Mid-life weight was more closely associated than weight at age 20 years with mid-life blood pressure. For a given mid-life weight, blood pressure was higher in persons with higher weight gain from age 20 years.CONCLUSION: In sum, weight gain between early adulthood and mid-life was associated with higher mid-life blood pressure. The magnitude of the association indicates a potentially great public health impact of strategies to prevent weight gain throughout adulthood.",

author = "Johan Sundstr{\"o}m and Lars Lind and Erik Lampa and Oskar Anger{\aa}s and Erasmus Bachus and G{\"o}ran Bergstr{\"o}m and Bo Carlberg and Gunnar Engstr{\"o}m and Engvall, {Jan E} and Mats Eriksson and Bruna Gigante and Emil Hagstr{\"o}m and Ola Hjelmgren and Jan-H{\aa}kan Jansson and Tomas Jernberg and Maria Mannila and Nystr{\"o}m, {Fredrik H} and Jonas Oldgren and Margaretha Persson and Anette Sandstr{\"o}m and Eva Swahn and Stefan S{\"o}derberg and Kjell Tor{\'e}n and {\"O}stgren, {Carl Johan} and Annika Rosengren",

year = "2020",

month = mar,

doi = "10.1097/HJH.0000000000002298",

language = "English",

volume = "38",

pages = "387--394",

journal = "Journal of Hypertension",

issn = "1473-5598",

publisher = "Lippincott Williams & Wilkins",

number = "3",

}

Sundström, J, Lind, L, Lampa, E, Angerås, O, Bachus, E, Bergström, G, Carlberg, B, Engström, G, Engvall, JE, Eriksson, M, Gigante, B, Hagström, E, Hjelmgren, O, Jansson, J-H, Jernberg, T, Mannila, M, Nyström, FH, Oldgren, J, Persson, M, Sandström, A, Swahn, E, Söderberg, S, Torén, K, Östgren, CJ & Rosengren, A 2020, 'Weight gain and blood pressure', Journal of Hypertension, vol. 38, no. 3, pp. 387-394. https://doi.org/10.1097/HJH.0000000000002298

TY - JOUR

T1 - Weight gain and blood pressure

AU - Sundström, Johan

AU - Lind, Lars

AU - Lampa, Erik

AU - Angerås, Oskar

AU - Bachus, Erasmus

AU - Bergström, Göran

AU - Carlberg, Bo

AU - Engström, Gunnar

AU - Engvall, Jan E

AU - Eriksson, Mats

AU - Gigante, Bruna

AU - Hagström, Emil

AU - Hjelmgren, Ola

AU - Jansson, Jan-Håkan

AU - Jernberg, Tomas

AU - Mannila, Maria

AU - Nyström, Fredrik H

AU - Oldgren, Jonas

AU - Persson, Margaretha

AU - Sandström, Anette

AU - Swahn, Eva

AU - Söderberg, Stefan

AU - Torén, Kjell

AU - Östgren, Carl Johan

AU - Rosengren, Annika

PY - 2020/3

Y1 - 2020/3

N2 - OBJECTIVE: Although the causality of the obesity--hypertension association is established, the potential for prevention is not. We hypothesized that weight gain between early adulthood and mid-life is associated with higher mid-life blood pressure.METHODS: We investigated the hypothesis using a large contemporaneous population-based mid-life cohort of men and women aged 50-64 years. Recalled body weight at age 20 years was self-reported, and mid-life body weight and office blood pressures were measured in accordance with a detailed protocol.RESULTS: On average, men had gained 14.9 (95% CI 14.6-15.2) kg of weight, and women 14.6 (95% CI 14.4-14.9) kg, between age 20 years and the mid-life examination, corresponding to 0.40 (95% CI 0.39-0.41) kg/year for men and women. Both weight at age 20 years and weight at the mid-life examination were associated with mid-life blood pressures. On average, a 10 kg weight increase between age 20 years and mid-life was associated with 2.2 (95% CI 0.9-3.5) mmHg higher systolic and 1.7 (95% CI 0.9-2.5) mmHg higher diastolic mid-life blood pressure in men, and 3.2 (2.5-4.0) mmHg higher systolic and 2.4 (1.9-2.9) mmHg higher diastolic mid-life blood pressure in women. Mid-life weight was more closely associated than weight at age 20 years with mid-life blood pressure. For a given mid-life weight, blood pressure was higher in persons with higher weight gain from age 20 years.CONCLUSION: In sum, weight gain between early adulthood and mid-life was associated with higher mid-life blood pressure. The magnitude of the association indicates a potentially great public health impact of strategies to prevent weight gain throughout adulthood.

AB - OBJECTIVE: Although the causality of the obesity--hypertension association is established, the potential for prevention is not. We hypothesized that weight gain between early adulthood and mid-life is associated with higher mid-life blood pressure.METHODS: We investigated the hypothesis using a large contemporaneous population-based mid-life cohort of men and women aged 50-64 years. Recalled body weight at age 20 years was self-reported, and mid-life body weight and office blood pressures were measured in accordance with a detailed protocol.RESULTS: On average, men had gained 14.9 (95% CI 14.6-15.2) kg of weight, and women 14.6 (95% CI 14.4-14.9) kg, between age 20 years and the mid-life examination, corresponding to 0.40 (95% CI 0.39-0.41) kg/year for men and women. Both weight at age 20 years and weight at the mid-life examination were associated with mid-life blood pressures. On average, a 10 kg weight increase between age 20 years and mid-life was associated with 2.2 (95% CI 0.9-3.5) mmHg higher systolic and 1.7 (95% CI 0.9-2.5) mmHg higher diastolic mid-life blood pressure in men, and 3.2 (2.5-4.0) mmHg higher systolic and 2.4 (1.9-2.9) mmHg higher diastolic mid-life blood pressure in women. Mid-life weight was more closely associated than weight at age 20 years with mid-life blood pressure. For a given mid-life weight, blood pressure was higher in persons with higher weight gain from age 20 years.CONCLUSION: In sum, weight gain between early adulthood and mid-life was associated with higher mid-life blood pressure. The magnitude of the association indicates a potentially great public health impact of strategies to prevent weight gain throughout adulthood.

U2 - 10.1097/HJH.0000000000002298

DO - 10.1097/HJH.0000000000002298

M3 - Article

C2 - 31764589

SN - 1473-5598

VL - 38

SP - 387

EP - 394

JO - Journal of Hypertension

JF - Journal of Hypertension

IS - 3

ER -

Weight gain and blood pressure

Abstract

Subject classification (UKÄ)

UN SDGs

Access to Document

Fingerprint

Cite this