TY - JOUR
T1 - Whole body composition analysis by the BodPod air-displacement plethysmography method in children with Phenylketonuria shows a higher body fat percentage
AU - Albersen, Monique
AU - Bonthuis, Marjolein
AU - De Roos, Nicole M.
AU - Van Den Hurk, Dorine A.M.
AU - Carbasius Weber, Ems
AU - Hendriks, Margriet M.W.B.
AU - De Sain-Van Der Velden, Monique G.M.
AU - De Koning, Tom J.
AU - Visser, Gepke
PY - 2010/1/1
Y1 - 2010/1/1
N2 - Background Phenylketonuria (PKU) causes irreversible central nervous system damage unless a phenylalanine (PHE) restricted diet with amino acid supplementation is maintained. To prevent growth retardation, a protein/amino acid intake beyond the recommended dietary protein allowance is mandatory. However, data regarding disease and/or diet related changes in body composition are inconclusive and retarded growth and/or adiposity is still reported. The BodPod whole body air-displacement plethysmography method is a fast, safe and accurate technique to measure body composition. Aim To gain more insight into the body composition of children with PKU. Methods Patients diagnosed with PKU born between 1991 and 2001 were included. Patients were identified by neonatal screening and treated in our centre. Body composition was measured using the BodPod system (Life Measurement Incorporation
AB - Background Phenylketonuria (PKU) causes irreversible central nervous system damage unless a phenylalanine (PHE) restricted diet with amino acid supplementation is maintained. To prevent growth retardation, a protein/amino acid intake beyond the recommended dietary protein allowance is mandatory. However, data regarding disease and/or diet related changes in body composition are inconclusive and retarded growth and/or adiposity is still reported. The BodPod whole body air-displacement plethysmography method is a fast, safe and accurate technique to measure body composition. Aim To gain more insight into the body composition of children with PKU. Methods Patients diagnosed with PKU born between 1991 and 2001 were included. Patients were identified by neonatal screening and treated in our centre. Body composition was measured using the BodPod system (Life Measurement Incorporation
UR - http://www.scopus.com/inward/record.url?scp=84897927846&partnerID=8YFLogxK
U2 - 10.1007/s10545-010-9149-8
DO - 10.1007/s10545-010-9149-8
M3 - Article
C2 - 20574715
AN - SCOPUS:84897927846
SN - 0141-8955
VL - 33
JO - Journal of Inherited Metabolic Disease
JF - Journal of Inherited Metabolic Disease
IS - SUPPL. 3
ER -