Bioorganic and Medicinal Chemistry, 0968-0896

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  1. 2018
  2. Novel multi-target compounds in the quest for new chemotherapies against Alzheimer's disease: An experimental and theoretical study

    Alberto Martínez, Mai Zahran, Miguel Gomez, Coreen Cooper, Johnny Guevara, Erik Ekengard, Ebbe Nordlander, Ralph Alcendor & Sarah Hambleton, 2018 Sep 15, In : Bioorganic and Medicinal Chemistry. 26, 17, p. 4823-4840 18 p.

    Research output: Contribution to journalArticle

  3. 2017
  4. Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide

    Jie Yang, Katarina Koruza, Zoë Fisher, Wolfgang Knecht & Lars Baltzer, 2017 Oct, In : Bioorganic and Medicinal Chemistry. 25, 20, p. 5838-5848

    Research output: Contribution to journalArticle

  5. Cystatin C peptidomimetic derivative with antimicrobial properties as a potential compound against wound infections

    Michał Pikuła, Maria Smuzyńska, Adam Krzystyniak, Maciej Zieliński, Paulina Langa, Milena Deptuła, Adriana Schumacher, Jakub Łata, Mirosława Cichorek, Anders Grubb, Piotr Trzonkowski, Franciszek Kasprzykowski & Sylwia Rodziewicz-Motowidło, 2017 Feb 15, In : Bioorganic and Medicinal Chemistry. 25, 4, p. 1431-1439 9 p.

    Research output: Contribution to journalArticle

  6. 2013
  7. Synthesis and biology of oligoethylene glycol linked naphthoxylosides.

    Karin Thorsheim, Andrea Persson, Richard Johnsson, Johanna Löfgren, Katrin Mani & Ulf Ellervik, 2013, In : Bioorganic & Medicinal Chemistry. 21, 11, p. 3310-3317

    Research output: Contribution to journalArticle

  8. 2011
  9. Synthesis, conformation and biology of naphthoxylosides.

    Anna Siegbahn, Ulrika Aili, Agata Ochocinska, Martin Olofsson, Jerk Rönnols, Katrin Mani, Göran Widmalm & Ulf Ellervik, 2011, In : Bioorganic & Medicinal Chemistry. 19, p. 4114-4126

    Research output: Contribution to journalArticle

  10. Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABA(A) receptors.

    Jakob Nilsson, Ritha Gidlöf, Elsebet Østergaard Nielsen, Tommy Liljefors, Mogens Nielsen & Olov Sterner, 2011, In : Bioorganic & Medicinal Chemistry. 19, 1, p. 111-121

    Research output: Contribution to journalArticle

  11. 2010
  12. Optimization of isochromanone based urotensin II receptor agonists

    Fredrik Lehmann, Erika A. Currier, Roger Olsson, Jian Nong Ma, Ethan S. Burstein, Uli Hacksell & Kristina Luthman, 2010 May 31, In : Bioorganic and Medicinal Chemistry. 18, 13, p. 4844-4854 11 p.

    Research output: Contribution to journalArticle

  13. 1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors

    Bader A. Salameh, Ian Cumpstey, Anders Sundin, Hakon Leffler & Ulf Nilsson, 2010, In : Bioorganic & Medicinal Chemistry. 18, 14, p. 5367-5378

    Research output: Contribution to journalArticle

  14. In vitro TRPV1 activity of piperine derived amides

    Edwin Andres Correa, Edward Högestätt, Olov Sterner, Fernando Echeverri & Peter Zygmunt, 2010, In : Bioorganic & Medicinal Chemistry. 18, 9, p. 3299-3306

    Research output: Contribution to journalArticle

  15. Photolabile ubiquinone analogues for identification and characterization of quinone binding sites in proteins.

    Zhichao Pei, Tobias Gustavsson, Robert Roth, Torbjörn Frejd & Cecilia Hägerhäll, 2010, In : Bioorganic & Medicinal Chemistry. 18, p. 3457-3466

    Research output: Contribution to journalArticle

  16. 2009
  17. Novel and potent small-molecule urotensin II receptor agonists

    Fredrik Lehmann, Erika A. Currier, Bryan Clemons, Lars K. Hansen, Roger Olsson, Uli Hacksell & Kristina Luthman, 2009 Jul 1, In : Bioorganic and Medicinal Chemistry. 17, 13, p. 4657-4665

    Research output: Contribution to journalArticle

  18. Synthesis and biological evaluation of reversible inhibitors of IdeS, a bacterial cysteine protease and virulence determinant

    Kristina Berggren, Björn Johansson, Tomas Fex, Jan Kihlberg, Lars Björck & Kristina Luthman, 2009, In : Bioorganic & Medicinal Chemistry. 17, 9, p. 3463-3470

    Research output: Contribution to journalArticle

  19. 2008
  20. Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABAA receptors.

    Erik Lager, Jakob Nilsson, Elsebet Østergaard Nielsen, Mogens Nielsen, Tommy Liljefors & Olov Sterner, 2008, In : Bioorganic & Medicinal Chemistry. 16, 14, p. 6936-6948

    Research output: Contribution to journalArticle

  21. Bioactive alkenylphenols from Piper obliquum.

    Carola Valdivia, Nieves Marquez, John Eriksson, Antonio Vilaseca, Eduardo Muñoz & Olov Sterner, 2008, In : Bioorganic & Medicinal Chemistry. 16, 7, p. 4120-4126

    Research output: Contribution to journalArticle

  22. Imidazo[1,2-a]pyridine derivatives as inhibitors of TNF-alpha expression in T cells

    Jan Rether, Gerhard Erkel, Timm Anke, Johan Eriksson Bajtner & Olov Sterner, 2008, In : Bioorganic & Medicinal Chemistry. 16, 3, p. 1236-1241

    Research output: Contribution to journalArticle

  23. SAR studies of capsazepinoid bronchodilators 3: The thiourea part (coupling region) and the 2-(4-chlorophenyl)ethyl moiety (C-region).

    Magnus Berglund, Maria Dalence, Staffan Skogvall & Olov Sterner, 2008, In : Bioorganic & Medicinal Chemistry. 16, 5, p. 2529-2540

    Research output: Contribution to journalArticle

  24. SAR studies of capsazepinoid bronchodilators. Part 1: The importance of the catechol moiety and aspects of the B-ring structure.

    Maria Dalence, Magnus Berglund, Staffan Skogvall & Olov Sterner, 2008, In : Bioorganic & Medicinal Chemistry. 16, 5, p. 2499-2512

    Research output: Contribution to journalArticle

  25. SAR studies of capsazepinoid bronchodilators. Part 2: Chlorination and catechol replacement in the A-ring.

    Magnus Berglund, Maria Dalence, Staffan Skogvall & Olov Sterner, 2008, In : Bioorganic & Medicinal Chemistry. 16, 5, p. 2513-2528

    Research output: Contribution to journalArticle

  26. Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A(4) hydrolase

    Thomas A. Kirkland, Marc Adler, John G. Bauman, Ming Chen, Jesper Z. Haeggstrom, Beverly King, Monica J. Kochanny, Amy M. Liang, Lisa Mendoza, Gary B. Phillips, Marjolein Thunnissen, Lan Trinh, Marc Whitlow, Bin Ye, Hong Ye, John Parkinson & William J. Guilford, 2008, In : Bioorganic & Medicinal Chemistry. 16, 9, p. 4963-4983

    Research output: Contribution to journalArticle

  27. 2007
  28. Construction of polyamine-modified uridine and adenosine derivatives-evaluation of DNA binding capacity and cytotoxicity in vitro

    Johannes Ghatnekar, Margareta Hägerlöf, Stina Oredsson, Kersti Alm, Sofi Elmroth & Tina Persson, 2007, In : Bioorganic & Medicinal Chemistry. 15, 23, p. 7426-7433

    Research output: Contribution to journalArticle

  29. Effects of oxygen-sulfur substitution on glycosaminoglycan-priming naphthoxylosides.

    Mårten Jacobsson, Katrin Mani & Ulf Ellervik, 2007, In : Bioorganic & Medicinal Chemistry. 15, 15, p. 5283-5299

    Research output: Contribution to journalArticle

  30. Synthesis and biology of bis-xylosylated dihydroxynaphthalenes.

    Richard Johnsson, Katrin Mani & Ulf Ellervik, 2007, In : Bioorganic & Medicinal Chemistry. 15, 8, p. 2868-2877

    Research output: Contribution to journalArticle

  31. 2006
  32. Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents

    KA Monk, R Siles, MB Hadimani, BE Mugabe, JF Ackley, SW Studerus, Klaus Edvardsen, ML Trawick, CM Garner, MR Rhodes, GR Pettit & KG Pinney, 2006, In : Bioorganic & Medicinal Chemistry. 14, 9, p. 3231-3244

    Research output: Contribution to journalArticle

  33. Side-chain and backbone amide bond requirements for glycopeptide stimulation of T-cells obtained in a mouse model for rheumatoid arthritis

    Lotta Holm, Robert Bockermann, Erik Wellner, Johan Bäcklund, Rikard Holmdahl & Jan Kihlberg, 2006, In : Bioorganic & Medicinal Chemistry. 14, 17, p. 5921-5932

    Research output: Contribution to journalArticle

  34. Synthesis of aromatic C-xylosides by position inversion of glucose

    Jesper Malmberg, Katrin Mani, Elin Säwén, Anders Wiren & Ulf Ellervik, 2006, In : Bioorganic & Medicinal Chemistry. 14, 19, p. 6659-6665

    Research output: Contribution to journalArticle

  35. Thioureido N-acetyllactosamine derivatives as potent galectin-7 and 9N inhibitors

    Bader Salameh, Anders Sundin, Hakon Leffler & Ulf Nilsson, 2006, In : Bioorganic & Medicinal Chemistry. 14, 4, p. 1215-1220

    Research output: Contribution to journalArticle

  36. 2005
  37. Isochromanone-based urotensin-II receptor agonists

    Fredrik Lehmann, Erika A. Currier, Roger Olsson, Uli Hacksell & Kristina Luthman, 2005 Apr 15, In : Bioorganic and Medicinal Chemistry. 13, 8, p. 3057-3068 12 p.

    Research output: Contribution to journalArticle

  38. Identification of the minimal glycopeptide core recognized by T cells in a model for rheumatoid arthritis

    L Holm, P Kjellen, Rikard Holmdahl & J Kihlberg, 2005, In : Bioorganic & Medicinal Chemistry. 13, 2, p. 473-482

    Research output: Contribution to journalArticle

  39. Tridemethylisovelleral, a potent cytotoxic agent

    Isabelle Aujard, Daniel Röme, Erwan Arzel, Martin H Johansson, D de Vos & Olov Sterner, 2005, In : Bioorganic & Medicinal Chemistry. 13, 22, p. 6145-6150

    Research output: Contribution to journalArticle

  40. 2003
  41. Quantitative studies of the binding of the class II PapG adhesin from uropathogenic Escherichia coli to oligosaccharides.

    A Larsson, Jörgen Ohlsson, K W Dodson, S J Hultgren, Ulf Nilsson & J Kihlberg, 2003, In : Bioorganic & Medicinal Chemistry. 11, 10, p. 2255-2261

    Research output: Contribution to journalArticle

  42. Role of the galactosyl moiety of collagen glycopeptides for T-cell stimulation in a model for rheumatoid arthritis

    B Holm, SM Baquer, L Holm, Rikard Holmdahl & J Kihlberg, 2003, In : Bioorganic & Medicinal Chemistry. 11, 18, p. 3981-3987

    Research output: Contribution to journalArticle

  43. 1998
  44. Reaction medium engineering in enzymatic peptide fragment condensation: Synthesis of eledoisin and LH-RH

    Peter Björup, Josep Lluís Torres, Patrick Adlercreutz & Pere Clapés, 1998 Jul 1, In : Bioorganic and Medicinal Chemistry. 6, 7, p. 891-901 11 p.

    Research output: Contribution to journalArticle

  45. 1996
  46. Synthesis of 2'-Deoxyuridine 5'-(α,β-Imido)triphosphate: A Substrate Analogue and Potent Inhibitor of dUTPase

    Tina Persson, Gunilla Larsson & Per-Olof Nyman, 1996, In : Bioorganic & Medicinal Chemistry. 4, 4, p. 553-556

    Research output: Contribution to journalArticle

  47. 1995
  48. Enzymatic peptide synthesis in low water content systems: Preparative enzymatic synthesis of [Leu]- and [Met]-enkephalin derivatives

    Pere Clapés, Josep Lluis Torres & Patrick Adlercreutz, 1995 Jan 1, In : Bioorganic and Medicinal Chemistry. 3, 3, p. 245-255 11 p.

    Research output: Contribution to journalArticle

  49. 1994
  50. Synthetic polymers as solubilizing vehicles for enzymes in water-poor media

    Patrick Adlercreutz, Bo Matiasson & Marina Otamiri, 1994 Jan 1, In : Bioorganic and Medicinal Chemistry. 2, 6, p. 529-533 5 p.

    Research output: Contribution to journalArticle