Diabetes, 1939-327X

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  1. Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes

    Abderrahmani, A., Yengo, L., Caiazzo, R., Canouil, M., Cauchi, S., Raverdy, V., Plaisance, V., Pawlowski, V., Lobbens, S., Maillet, J., Rolland, L., Boutry, R., Queniat, G., Kwapich, M., Tenenbaum, M., Bricambert, J., Saussenthaler, S., Anthony, E., Jha, P., Derop, J. & 18 othersSand, O., Rabearivelo, I., Leloire, A., Pigeyre, M., Daujat-Chavanieu, M., Gerbal-Chaloin, S., Dayeh, T., Lassailly, G., Mathurin, P., Staels, B., Auwerx, J., Schürmann, A., Postic, C., Schafmayer, C., Hampe, J., Bonnefond, A., Pattou, F. & Froguel, P., 2018 Jul 1, In : Diabetes. 67, 7, p. 1310-1321 12 p.

    Research output: Contribution to journalArticle

  2. GAD65-specific autoantibodies enhance the presentation of an immunodominant T-cell epitope from GAD65

    af Hällström-Reijonen, C., Daniels, T. L., A. Lernmark & Nepom, G. T., 2000, In : Diabetes. 49, 10, p. 1621-1626 6 p.

    Research output: Contribution to journalArticle

  3. The effect of pronounced hypoglycemia on monoamine metabolism in rat brain

    Agardh, C-D., Carlsson, A., Linqvist, M. & Siesjö, B., 1979, In : Diabetes. 28, 9, p. 804-809

    Research output: Contribution to journalArticle

  4. A link between GIP and osteopontin in adipose tissue and insulin resistance.

    Ahlqvist, E., Osmark, P., Kuulasmaa, T., Pilgaard, K., Omar, B., Brøns, C., Kotova, O., Zetterqvist, A., Stancáková, A., Jonsson, A., Hansson, O., Kuusisto, J., Kieffer, T. J., Tuomi, T., Isomaa, B., Madsbad, S., Gomez, M. F., Poulsen, P., Laakso, M., Degerman, E. & 5 othersPihlajamäki, J., Nils Wierup, Allan Vaag, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 6, p. 2088-2094

    Research output: Contribution to journalArticle

  5. Hepato-Incretin Function of GLP-1: Novel Concept and Target in Type 1 Diabetes.

    Bo Ahrén, 2015, In : Diabetes. 64, 3, p. 715-717

    Research output: Contribution to journalDebate/Note/Editorial

  6. Neuropeptides and the regulation of islet function.

    Bo Ahrén, Nils Wierup & Sundler, F., 2006, In : Diabetes. 55, Suppl 2, p. S98-S107

    Research output: Contribution to journalArticle

  7. Quantification of insulin secretion in relation to insulin sensitivity in nondiabetic postmenopausal women.

    Bo Ahrén & Larsson, H., 2002, In : Diabetes. 51, Suppl 1, p. S202-S211

    Research output: Contribution to journalArticle

  8. Metabolite profiling of LADA challenges the view of a metabolically distinct subtype

    Al-Majdoub, M., Ali, A., Storm, P., Anders H. Rosengren, Leif Groop & Peter Spégel, 2017 Apr 1, In : Diabetes. 66, 4, p. 806-814 9 p.

    Research output: Contribution to journalArticle

  9. Antidiabetic Actions of an Estrogen Receptor beta Selective Agonist

    Alonso-Magdalena, P., Ropero, A. B., Garcia-Arevalo, M., Soriano, S., Quesada, I., Jabar Muhammed, S., S Albert Salehi, Gustafsson, J-A. & Nadal, A., 2013, In : Diabetes. 62, 6, p. 2015-2025

    Research output: Contribution to journalArticle

  10. Glutamine-elicited secretion of glucagon-like peptide 1 is governed by an activated glutamate dehydrogenase

    Andersson, L. E., Liliya Shcherbina, Al-Majdoub, M., Neelanjan Vishnu, Arroyo, C. B., Carrara, J. A., Claes B. Wollheim, Malin Fex, Hindrik Mulder, Nils Wierup & Peter Spégel, 2018 Mar 1, In : Diabetes. 67, 3, p. 372-384 13 p.

    Research output: Contribution to journalArticle

  11. MafA and MafB Regulate Genes Critical to beta-Cells in a Unique Temporal Manner

    Isabella Artner, Hang, Y., Mazur, M., Yamamoto, T., Guo, M., Lindner, J., Magnuson, M. A. & Stein, R., 2010, In : Diabetes. 59, 10, p. 2530-2539

    Research output: Contribution to journalArticle

  12. Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells

    Barg, S., Galvanovskis, J., Gopel, S. O., Rorsman, P. & Lena Eliasson, 2000, In : Diabetes. 49, 9, p. 1500-1510

    Research output: Contribution to journalArticle

  13. Hepatic DPP4 DNA methylation associates with fatty liver

    Baumeier, C., Saussenthaler, S., Kammel, A., Jähnert, M., Schlüter, L., Hesse, D., Canouil, M., Lobbens, S., Caiazzo, R., Raverdy, V., Pattou, F., Nilsson, E., Pihlajamäki, J., Charlotte Ling, Froguel, P., Schürmann, A. & Schwenk, R. W., 2017 Jan 1, In : Diabetes. 66, 1, p. 25-35 11 p.

    Research output: Contribution to journalArticle

  14. Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

    Berglund, L., Lyssenko, V., Ladenvall, C., Kotova, O., Edsfeldt, A., Pilgaard, K., Alkayyali, S., Brøns, C., Forsblom, C., Jonsson, A., Zetterqvist, A., Nitulescu, M., Ruiz McDavitt, C., Dunér, P., Stancáková, A., Kuusisto, J., Ahlqvist, E., Lajer, M., Tarnow, L., Madsbad, S. & 13 othersRossing, P., Kieffer, T. J., Olle Melander, Marju Orho-Melander, Peter Nilsson, Groop, P-H., Allan Vaag, Lindblad, B., Anders Gottsäter, Laakso, M., Isabel Goncalves, Leif Groop & Maria Gomez, 2016, In : Diabetes. 65, 1, p. 239-254

    Research output: Contribution to journalArticle

  15. Growth hormone overexpression in the central nervous system results in hyperphagia-induced obesity associated with insulin resistance and dyslipidemia

    Bohlooly, M., Olsson, B., Bruder, CEG., Linden, D., Sjogren, K., Bjursell, M., Egecioglu, E., Svensson, L., Brodin, P., Waterton, JC., Isaksson, OGP., Sundler, F., Bo Ahrén, Ohlsson, C., Oscarsson, J. & Tornell, J., 2005, In : Diabetes. 54, 1, p. 51-62

    Research output: Contribution to journalArticle

  16. Association of IDDM and attenuated response of 2',5'-oligoadenylate synthetase to yellow fever vaccine

    Bonnevie-Nielsen, V., Larsen, M. L., Frifelt, J. J., Michelsen, B. & A. Lernmark, 1989 Jan 1, In : Diabetes. 38, 12, p. 1636-1642

    Research output: Contribution to journalArticle

  17. A major loss in islet mass and b-cell function precedes hyperglycemia in mice given multiple low doses of streptozotocin

    Bonnevie-Nielsen, V., Steffes, M. W. & A. Lernmark, 1981 Jan 1, In : Diabetes. 30, 5, p. 424-429

    Research output: Contribution to journalArticle

  18. The SNARE Protein SNAP23 and the SNARE-Interacting Protein Munc18c in Human Skeletal Muscle Are Implicated in Insulin Resistance/Type 2 Diabetes

    Bostrom, P., Andersson, L., Vind, B., Haversen, L., Rutberg, M., Wickstrom, Y., Larsson, E., Jansson, P-A., Svensson, M. K., Branemark, R., Charlotte Ling, Beck-Nielsen, H., Boren, J., Hojlund, K. & Olofsson, S-O., 2010, In : Diabetes. 59, 8, p. 1870-1878

    Research output: Contribution to journalArticle

  19. Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing {beta}-Cell-Like Cells.

    Brolén, G., Heins, N., Edsbagge, J. & Semb, H., 2005, In : Diabetes. 54, 10, p. 2867-2874

    Research output: Contribution to journalArticle

  20. Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation

    Cabric, S., Sanchez, J., Lundgren, T., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibell, A., Tufveson, G., Larsson, R., Korsgren, O. & Nilsson, B., 2007, In : Diabetes. 56, 8, p. 2008-2015

    Research output: Contribution to journalArticle

  21. Association studies of BMI and type 2 diabetes in the neuropeptide y pathway - A possible role for NPY2R as a candidate gene for type 2 diabetes in men

    Campbell, C. D., Lyon, H. N., Nemesh, J., Drake, J. A., Tuomi, T., Gaudet, D., Zhu, X., Cooper, R. S., Ardlie, K. G., Leif Groop & Hirschhorn, J. N., 2007, In : Diabetes. 56, 5, p. 1460-1467

    Research output: Contribution to journalArticle

  22. Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes

    Cervin, C., Valeriya Lyssenko, Bakhtadze, E., Eero Lindholm, Peter Nilsson, Tuomi, T., Corrado Cilio & Leif Groop, 2008, In : Diabetes. 57, 5, p. 1433-1437

    Research output: Contribution to journalArticle

  23. Cosegregation of MIDD and MODY in a Pedigree: Functional and Clinical Consequences.

    Cervin, C., Liljeström, B., Tuomi, T., Heikkinen, S., Tapanainen, J. S., Leif Groop & Corrado Cilio, 2004, In : Diabetes. 53, 7, p. 1894-1899

    Research output: Contribution to journalArticle

  24. Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion

    Collins, S. C., Do, H. W., Hastoy, B., Hugill, A., Adam, J., Chibalina, M. V., Galvanovskis, J., Godazgar, M., Lee, S., Goldsworthy, M., S Albert Salehi, Tarasov, A. I., Anders H. Rosengren, Cox, R. & Rorsman, P., 2016 Jul 1, In : Diabetes. 65, 7, p. 1952-1961 10 p.

    Research output: Contribution to journalArticle

  25. Type 1 Diabetes: Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families.

    Concannon, P., Erlich, HA., Julier, C., Morahan, G., Nerup, J., Pociot, F., Todd, JA., Rich, SS., Type 1 Diabetes Genetics Consortium, T. & Joyce Carlson, 2005, In : Diabetes. 54, p. 2995-3001

    Research output: Contribution to journalArticle

  26. Aged Transgenic Mice With Increased Glucocorticoid Sensitivity in Pancreatic beta-Cells Develop Diabetes.

    Davani, B., Portwood, N., Bryzgalova, G., Reimer, M. K., Heiden, T., Ostenson, C-G., Okret, S., Bo Ahrén, Efendic, S. & Khan, A., 2004, In : Diabetes. 53, Suppl 1, p. S51-S59

    Research output: Contribution to journalArticle

  27. Impact of an Exercise Intervention on DNA Methylation in Skeletal Muscle From First-Degree Relatives of Patients With Type 2 Diabetes.

    Dekker Nitert, M., Dayeh, T., Volkov, P., Elgzyri, T., Hall, E., Nilsson, E., Yang, B., Lang, S., Parikh, H., Wessman, Y., Weishaupt, H., Attema, J., Abels, M., Wierup, N., Almgren, P., Jansson, P-A., Rönn, T., Hansson, O., Eriksson, K-F., Groop, L. & 1 othersCharlotte Ling, 2012, In : Diabetes.

    Research output: Contribution to journalArticle

  28. Zinc Transporter 8 Autoantibodies and Their Association With SLC30A8 and HLA-DQ Genes Differ Between Immigrant and Swedish Patients With Newly Diagnosed Type 1 Diabetes in the Better Diabetes Diagnosis Study.

    Delli, A., Vaziri Sani, F., Lindblad, B., Helena Larsson, Annelie Carlsson, Forsander, G., Sten Ivarsson, Ludvigsson, J., Kockum, I., Marcus, C., Samuelsson, U., Ortqvist, E., Leif Groop, Bondinas, G. P., Papadopoulos, G. K. & Åke Lernmark, 2012, In : Diabetes. 61, 10, p. 2556-2564

    Research output: Contribution to journalArticle

  29. Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism

    Ding, W. G., Erik Renström, Rorsman, P., Buschard, K. & Gromada, J., 1997, In : Diabetes. 46, 5, p. 792-800

    Research output: Contribution to journalArticle

  30. The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human.

    E, K., N, K., R, K., J, W., CM, O., E, W., Dan Holmberg, S, C. & L, S., 2013, In : Diabetes. 62, 2, p. 531-542

    Research output: Contribution to journalArticle

  31. A unique defect in the regulation of visceral fat cell lipolysis in the polycystic ovary syndrome as an early link to insulin resistance

    Ek, I., Arner, P., Ryden, M., Cecilia Holm, Thorne, A., Hoffstedt, J. & Wahrenberg, H., 2002, In : Diabetes. 51, 2, p. 484-492

    Research output: Contribution to journalArticle

  32. 5 ' flanking variants of resistin are associated with obesity

    Engert, JC., Vohl, MC., Williams, SM., Lepage, P., Loredo-Osti, JC., Faith, J., Dore, C., Renaud, Y., Burtt, NP., Villeneuve, A., Hirschhorn, JN., Altshuler, D., Leif Groop, Despres, JP., Gaudet, D. & Hudson, TJ., 2002, In : Diabetes. 51, 5, p. 1629-1634

    Research output: Contribution to journalArticle

  33. Inflammation-sensitive plasma proteins are associated with future weight gain.

    Gunnar Engström, Bo Hedblad, Stavenow, L., Lind, P., Janzon, L. & Lindgärde, F., 2003, In : Diabetes. 52, 8, p. 2097-2101

    Research output: Contribution to journalArticle

  34. Complement c3 is a risk factor for the development of diabetes: a population-based cohort study.

    Gunnar Engström, Bo Hedblad, Karl-Fredrik Eriksson, Janzon, L. & Lindgärde, F., 2005, In : Diabetes. 54, 2, p. 570-575

    Research output: Contribution to journalArticle

  35. Inflammation-sensitive plasma proteins, diabetes, and mortality and incidence of myocardial infarction and stroke: a population-based study.

    Gunnar Engström, Stavenow, L., Bo Hedblad, Lind, P., Karl-Fredrik Eriksson, Janzon, L. & Lindgärde, F., 2003, In : Diabetes. 52, 2, p. 442-447

    Research output: Contribution to journalArticle

  36. HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: Analysis of the Type 1 Diabetes Genetics Consortium families

    Erlich, H., Valdes, A. M., Noble, J., Joyce Carlson, Varney, M., Concannon, P., Mychaleckyj, J. C., Todd, J. A., Bonella, P., Fear, A. L., Lavant, E., Louey, A. & Moonsamy, P., 2008, In : Diabetes. 57, 4, p. 1084-1092

    Research output: Contribution to journalArticle

  37. Insulin resistance is accompanied by increased fasting glucagon and delayed glucagon suppression in individuals with normal and impaired glucose regulation

    Færch, K., Vistisen, D., Pacini, G., Torekov, S. S., Johansen, N. B., Witte, D. R., Jonsson, A., Pedersen, O., Hansen, T., Lauritzen, T., Jørgensen, M. E., Bo Ahrén & Holst, J. J., 2016 Nov 1, In : Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journalArticle

  38. Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors.

    Fall, T., Hägg, S., Ploner, A., Mägi, R., Fischer, K., Draisma, H. H. M., Sarin, A-P., Benyamin, B., Ladenvall, C., Åkerlund, M., Kals, M., Esko, T., Nelson, C. P., Kaakinen, M., Huikari, V., Mangino, M., Meirhaeghe, A., Kristiansson, K., Nuotio, M-L., Kobl, M. & 68 othersGrallert, H., Dehghan, A., Kuningas, M., de Vries, P. S., de Bruijn, R. F. A. G., Willems, S. M., Heikkilä, K., Silventoinen, K., Pietiläinen, K. H., Legry, V., Giedraitis, V., Goumidi, L., Syvänen, A-C., Strauch, K., Koenig, W., Lichtner, P., Herder, C., Palotie, A., Menni, C., Uitterlinden, A. G., Kuulasmaa, K., Havulinna, A. S., Moreno, L. A., Gonzalez-Gross, M., Evans, A., Tregouet, D-A., Yarnell, J. W. G., Virtamo, J., Ferrières, J., Veronesi, G., Perola, M., Arveiler, D., Brambilla, P., Lind, L., Kaprio, J., Hofman, A., Stricker, B. H., van Duijn, C. M., Ikram, M. A., Franco, O. H., Cottel, D., Dallongeville, J., Hall, A. S., Jula, A., Tobin, M. D., Penninx, B. W., Peters, A., Gieger, C., Samani, N. J., Montgomery, G. W., Whitfield, J. B., Martin, N. G., Leif Groop, Spector, T. D., Magnusson, P. K., Amouyel, P., Boomsma, D. I., Peter Nilsson, Järvelin, M-R., Valeriya Lyssenko, Metspalu, A., Strachan, D. P., Salomaa, V., Ripatti, S., Pedersen, N. L., Prokopenko, I., McCarthy, M. I. & Ingelsson, E., 2015, In : Diabetes. 64, 5, p. 1841-1852

    Research output: Contribution to journalArticle

  39. Using genetic variants to assess the relationship between circulating lipids and type 2 diabetes.

    Fall, T., Xie, W., Poon, W., Yaghootkar, H., Mägi, R., Knowles, J. W., Valeriya Lyssenko, Weedon, M., Frayling, T. M. & Ingelsson, E., 2015, In : Diabetes. 64, 7, p. 2676-2684

    Research output: Contribution to journalArticle

  40. Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance

    Ferrannini, E., Natali, A., Camastra, S., Nannipieri, M., Mari, A., Adam, K-P., Milburn, M. V., Kastemmueller, G., Adamski, J., Tuomi, T., Valeriya Lyssenko, Leif Groop & Gall, W. E., 2013, In : Diabetes. 62, 5, p. 1730-1737

    Research output: Contribution to journalArticle

  41. {beta}-Cell Lipases and Insulin Secretion.

    Malin Fex, Lucas, S., Sörhede Winzell, M., Bo Ahrén, Cecilia Holm & Hindrik Mulder, 2006, In : Diabetes. 55, Suppl 2, p. S24-S31

    Research output: Contribution to journalArticle

  42. A global overview of precision medicine in type 2 diabetes

    Hugo Fitipaldi, McCarthy, M. I., Florez, J. C. & Paul W. Franks, 2018, In : Diabetes. 67, 10, p. 1911-1922 12 p.

    Research output: Contribution to journalReview article

  43. Activation of enteroendocrine membrane progesterone receptors promotes incretin secretion and improves glucose tolerance in mice

    Flock, G. B., Cao, X., Marlena Maziarz & Drucker, D. J., 2013 Jan 1, In : Diabetes. 62, 1, p. 283-290 8 p.

    Research output: Contribution to journalArticle

  44. High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

    Florez, JC., Wiltshire, S., Agapakis, CM., Burtt, NP., de Bakker, PIW., Almgren, P., Bostrom, KB., Tuomi, T., Gaudet, D., Daly, MJ., Hirschhorn, JN., McCarthy, MI., Altshuler, D. & Leif Groop, 2006, In : Diabetes. 55, 1, p. 128-135

    Research output: Contribution to journalArticle

  45. Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people

    Florez, J. C., Agapakis, C. M., Burtt, N. P., Sun, M., Almgren, P., Lennart Råstam, Tuomi, T., Gaudet, D., Hudson, T. J., Daly, M. J., Ardlie, K. G., Hirschhorn, J. N., Leif Groop & Altshuler, B., 2005, In : Diabetes. 54, 6, p. 1884-1891

    Research output: Contribution to journalArticle

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