Diabetes, 1939-327X

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  1. Association testing of the protein tyrosine phosphatase 1B gene (PTPN1) with type 2 diabetes in 7,883 people

    Florez, J. C., Agapakis, C. M., Burtt, N. P., Sun, M., Almgren, P., Lennart Råstam, Tuomi, T., Gaudet, D., Hudson, T. J., Daly, M. J., Ardlie, K. G., Hirschhorn, J. N., Leif Groop & Altshuler, B., 2005, In : Diabetes. 54, 6, p. 1884-1891

    Research output: Contribution to journalArticle

  2. Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium Channel Gene Region.

    Florez, J. C., Burtt, N., De Bakker, P. I. W., Almgren, P., Tuomi, T., Holmkvist, J., Gaudet, D., Hudson, T. J., Schaffner, S. F., Daly, M. J., Hirschhorn, J. N., Leif Groop & Altshuler, D., 2004, In : Diabetes. 53, 5, p. 1360-1368

    Research output: Contribution to journalArticle

  3. The Kruppel-like factor 11 (KLF11) Q62R polymorphism is not associated with type 2 diabetes in 8,676 people

    Florez, J. C., Saxena, R., Winckler, W., Burtt, N. P., Almgren, P., Kristina Bengtsson Boström, Tuomi, T., Gaudet, D., Ardlie, K. G., Daly, M. J., Altshuler, D., Hirschhorn, J. N. & Leif Groop, 2006, In : Diabetes. 55, 12, p. 3620-3624

    Research output: Contribution to journalArticle

  4. Association testing in 9,000 people fails to confirm the association of the insulin receptor substrate-1 G972R polymorphism with type 2 diabetes

    Florez, JC., Marketa Sjögren, Burtt, N., Marju Orho-Melander, Schayer, S., Sun, M., Almgren, P., Lindblad, U., Tuomi, T., Gaudet, D., Hudson, TJ., Daly, MJ., Ardlie, KG., Hirschhorn, JN., Altshuler, D. & Leif Groop, 2004, In : Diabetes. 53, 12, p. 3313-3318

    Research output: Contribution to journalArticle

  5. Diabetes family history: a metabolic storm you should not sit out.

    Paul Franks, 2010, In : Diabetes. 59, p. 2732-2734

    Research output: Contribution to journalArticle

  6. Using genotype-based recall to estimate the effects of amy1 copy number variation in substrate metabolism

    Paul W. Franks & Frida Renström, 2016 Nov 1, In : Diabetes. 65, 11, p. 3240-3242 3 p.

    Research output: Contribution to journalDebate/Note/Editorial

  7. A Genome-Wide Scan in Families With Maturity-Onset Diabetes of the Young: Evidence for Further Genetic Heterogeneity.

    Frayling, T. M., Lindgren, C., Chevre, J. C., Menzel, S., Wishart, M., Benmezroua, Y., Brown, A., Evans, J. C., Rao, P. S., Dina, C., Lecoeur, C., Kanninen, T., Almgren, P., Bulman, M. P., Wang, Y., Mills, J., Wright-Pascoe, R., Mahtani, M. M., Prisco, F., Costa, A. & 9 othersCognet, I., Hansen, T., Pedersen, O., Ellard, S., Tuomi, T., Leif Groop, Froguel, P., Hattersley, A. T. & Vaxillaire, M., 2003, In : Diabetes. 52, 3, p. 872-881

    Research output: Contribution to journalArticle

  8. Introgression of F344 rat genomic DNA on BB rat chromosome 4 generates diabetes-resistant lymphopenic BB rats.

    Fuller, J., Kwitek, A. E., Hawkins, T. J., Moralejo, D. H., Lu, W., Tupling, T. D., Macmurray, A. J., Borchardt, G., Hasinoff, M. & Åke Lernmark, 2006, In : Diabetes. 55, p. 3351-3357

    Research output: Contribution to journalArticle

  9. Meta-Immunological Profiling of Children With Type 1 Diabetes Identifies New Biomarkers to Monitor Disease Progression

    Galgani, M., Nugnes, R., Bruzzese, D., Perna, F., De Rosa, V., Procaccini, C., Mozzillo, E., Corrado Cilio, Helena Larsson, Åke Lernmark, La Cava, A., Franzese, A. & Matarese, G., 2013, In : Diabetes. 62, 7, p. 2481-2491

    Research output: Contribution to journalArticle

  10. Mature-onset obesity in interleukin-1 receptor I knockout mice

    Garcia, MC., Wernstedt, I., Berndtsson, A., Enge, M., Bell, M., Hultgren, O., Horn, M., Bo Ahrén, Enerback, S., Ohlsson, C., Wallenius, V. & Jansson, JO., 2006, In : Diabetes. 55, 5, p. 1205-1213

    Research output: Contribution to journalArticle

  11. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes.

    Graham, J., Hagopian, WA., Kockum, I., Li, LS., Sanjeevi, CB., Lowe, RM., Schaefer, JB., Zarghami, M., Day, HL., Mona Landin-Olsson, Palmer, JP., Janer-Villanueva, M., Hood, L., Sundkvist, G., Åke Lernmark, Breslow, N., Dahlquist, G. & Blohme, G., 2002, In : Diabetes. 51, 5, p. 1346-1355

    Research output: Contribution to journalArticle

  12. Improved specificity of ICA assays in the Fourth International Immunology of Diabetes Serum Exchange Workshop

    Greenbaum, C. J., Palmer, J. P., Nagataki, S., Yamaguchi, Y., Molenaar, J. L., Van Beers, W. A. M., Maclaren, N. K., A. Lernmark, Villena, A. A., Barbosa, J., DeBeaufort, C., Becker, D., Becker, F., Betterle, C., Bosi, E., Bottazzo, G. F., Bright, G., Colman, P. & Dawkins, R. L., 1992 Jan 1, In : Diabetes. 41, 12, p. 1570-1574

    Research output: Contribution to journalArticle

  13. Metabolic and underlying causes of diabetes mellitus

    Grodsky, G. M., Anderson, C. E., Coleman, D. L., Craighead, J. E., Gerritsen, G. C., Hansen, C. T., Herberg, L., Howard, C. F., A. Lernmark, Matschinsky, F. M., Rayfield, E., Riley, W. J. & Rossini, A. A., 1982 Dec 4, In : Diabetes. 31, Suppl. 1, p. 45-53 9 p.

    Research output: Contribution to journalArticle

  14. Glucagon-like peptide I increases cytoplasmic calcium in insulin-secreting beta TC3-cells by enhancement of intracellular calcium mobilization

    Gromada, J., Dissing, S., Bokvist, K., Erik Renström, Frokjaer-Jensen, J., Wulff, B. S. & Rorsman, P., 1995, In : Diabetes. 44, 7, p. 767-774

    Research output: Contribution to journalArticle

  15. Regulation and Function of FTO mRNA Expression in Human Skeletal Muscle and Subcutaneous Adipose Tissue

    Grunnet, L. G., Nilsson, E., Charlotte Ling, Hansen, T., Pedersen, O., Leif Groop, Vaag, A. & Poulsen, P., 2009, In : Diabetes. 58, 10, p. 2402-2408

    Research output: Contribution to journalArticle

  16. Autoantibodies in IDDM primarily recognize the 65,000-Mr rather than the 67,000-Mr isoform of glutamic acid decarboxylase

    Hagopian, W. A., Michelsen, B., Karlsen, A. E., Larsen, F., Moody, A., Grubin, C. E., Rowe, R., Petersen, J., Mcevoy, R. & Åke Lernmark, 1993 Jan 1, In : Diabetes. 42, 4, p. 631-636

    Research output: Contribution to journalArticle

  17. Gene and Cell-Replacement Therapy in the Treatment of Type 1 Diabetes: How High Must the Standards Be Set?

    Halban, P. A., Kahn, S. E., Åke Lernmark & Rhodes, C. J., 2001 Oct, In : Diabetes. 50, 10, p. 2181-2191 11 p.

    Research output: Contribution to journalReview article

  18. Adrenaline Stimulates Glucagon Secretion by Tpc2-Dependent Ca2+ Mobilization From Acidic Stores in Pancreatic α-Cells

    Alexander Hamilton, Zhang, Q., Albert Salehi, Willems, M., Knudsen, J. G., Ringgaard, A. K., Chapman, C. E., Gonzalez-Alvarez, A., Surdo, N. C., Zaccolo, M., Basco, D., Johnson, P. R. V., Ramracheya, R., Rutter, G. A., Galione, A., Rorsman, P. & Tarasov, A. I., 2018 Jun, In : Diabetes. 67, 6, p. 1128-1139 12 p.

    Research output: Contribution to journalArticle

  19. In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse - Pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells

    Henquin, JC., Nenquin, M., Stiernet, P. & Bo Ahrén, 2006, In : Diabetes. 55, 2, p. 441-451

    Research output: Contribution to journalArticle

  20. FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies

    Hertel, J. K., Johansson, S., Emily Sonestedt, Jonsson, A., Lie, R. T., Platou, C. G. P., Peter Nilsson, Rukh, G., Midthjell, K., Hveem, K., Olle Melander, Leif Groop, Valeriya Lyssenko, Molven, A., Marju Orho-Melander & Njolstad, P. R., 2011, In : Diabetes. 60, 5, p. 1637-1644

    Research output: Contribution to journalArticle

  21. Lifestyle and metformin ameliorate insulin sensitivity independently of the genetic burden of established insulin resistance variants in Diabetes Prevention Program participants.

    Hivert, M-F., Christophi, C. A., Paul Franks, Jablonski, K. A., Ehrmann, D. A., Kahn, S. E., Horton, E. S., Pollin, T. I., Mather, K. J., Perreault, L., Barrett-Connor, E., Knowler, W. C. & Florez, J. C., 2016 Feb, In : Diabetes. 65, 2, p. 520-526

    Research output: Contribution to journalArticle

  22. Updated Genetic Score Based on 34 Confirmed Type 2 Diabetes Loci Is Associated With Diabetes Incidence and Regression to Normoglycemia in the Diabetes Prevention Program

    Hivert, M-F., Jablonski, K. A., Perreault, L., Saxena, R., McAteer, J. B., Paul Franks, Hamman, R. F., Kahn, S. E., Haffner, S., Meigs, J. B., Altshuler, D., Knowler, W. C. & Florez, J. C., 2011, In : Diabetes. 60, 4, p. 1340-1348

    Research output: Contribution to journalArticle

  23. Interaction and association analysis of a type 1 diabetes susceptibility locus on chromosome 5q11-q13 and the 7q32 chromosomal region in Scandinavian families

    Holm, P., Rydlander, B., Holger Luthman & Kockum, I., 2004, In : Diabetes. 53, 6, p. 1584-1591

    Research output: Contribution to journalArticle

  24. Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes

    Holmkvist, J., Almgren, P., Lyssenko, V., Lindgren, C. M., Karl-Fredrik Eriksson, Isomaa, B., Tuomi, T., Peter Nilsson & Leif Groop, 2008, In : Diabetes. 57, 6, p. 1738-1744

    Research output: Contribution to journalArticle

  25. Bariatric surgery enhances splanchnic vascular responses in patients with type 2 diabetes

    Honka, H., Koffert, J., Kauhanen, S., Teuho, J., Hurme, S., Mari, A., Andreas Lindqvist, Nils Wierup, Leif Groop & Nuutila, P., 2017 Apr 1, In : Diabetes. 66, 4, p. 880-885 6 p.

    Research output: Contribution to journalArticle

  26. Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.

    Huang, X., Vaag, A., Emma A Nilsson, Hansson, M., Bo Ahrén & Leif Groop, 2003, In : Diabetes. 52, 9, p. 2411-2418

    Research output: Contribution to journalArticle

  27. Interferon expression in the pancreases of patients with type I diabetes

    Huang, X., Yuan, J., Goddard, A., Foulis, A., James, R. F. L., Åke Lernmark, Pujol-Borrell, R., Rabinovitch, A., Somoza, N. & Stewart, T. A., 1995 Jan 1, In : Diabetes. 44, 6, p. 658-664

    Research output: Contribution to journalArticle

  28. Quantitative determination of islet cell surface antibodies using 125I-protein A

    Huen, A. H. J., Haneda, M., Freedman, Z., A. Lernmark & Rubenstein, A. H., 1983 Jun 16, In : Diabetes. 32, 5 I, p. 460-465 6 p.

    Research output: Contribution to journalArticle

  29. IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies

    Huth, C., Heid, I. M., Vollmert, C., Gieger, C., Grallert, H., Wolford, J. K., Langer, B., Thorand, B., Klopp, N., Hamid, Y. H., Pedersen, O., Hansen, T., Lyssenko, V., Groop, L., Meisinger, C., Doring, A., Lowel, H., Lieb, W., Hengstenberg, C., Rathmann, W. & 25 othersMartin, S., Stephens, J. W., Ireland, H., Mather, H., Miller, G. J., Stringham, H. M., Boehnke, M., Tuomilehto, J., Boeing, H., Mohlig, M., Spranger, J., Pfeiffer, A., Wernstedt, I., Niklason, A., Lopez-Bermejo, A., Fernandez-Real, J-M., Hanson, R. L., Gallart, L., Vendrell, J., Tsiavou, A., Hatziagelaki, E., Humphries, S. E., Wichmann, H. -E., Herder, C. & Illig, T., 2006, In : Diabetes. 55, 10, p. 2915-2921

    Research output: Contribution to journalArticle

  30. Redox control of exocytosis - Regulatory role of NADPH, thioredoxin, and glutaredoxin

    Ivarsson, R., Quintens, R., Dejonghe, S., Tsukamoto, K., Veld, P., Erik Renström & Schuit, FC., 2005, In : Diabetes. 54, 7, p. 2132-2142

    Research output: Contribution to journalArticle

  31. Nonislet pancreatic autoantibodies in sibship with permanent neonatal insulin-dependent diabetes mellitus

    Ivarsson, S. A., Marner, B., A. Lernmark & Nilsson, K. O., 1988 Jan 1, In : Diabetes. 37, 3, p. 347-350 4 p.

    Research output: Contribution to journalArticle

  32. Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program

    Jablonski, K. A., McAteer, J. B., de Bakker, P. I., Paul Franks, Pollin, T. I., Hanson, R. L., Saxena, R., Fowler, S., Shuldiner, A. R., Knowler, W. C., Altshuler, D. & Florez, J. C., 2010, In : Diabetes. Oct, 59(10), p. 2672-2681

    Research output: Contribution to journalArticle

  33. Genome-wide and abdominal MRI data provide evidence that a genetically determined favorable adiposity phenotype is characterized by lower ectopic liver fat and lower risk of type 2 diabetes, heart disease, and hypertension

    Ji, Y., Yiorkas, A. M., Frau, F., Mook-Kanamori, D., Staiger, H., Thomas, E. L., Atabaki-Pasdar, N., Campbell, A., Tyrrell, J., Jones, S. E., Beaumont, R. N., Wood, A. R., Tuke, M. A., Ruth, K. S., Mahajan, A., Murray, A., Freathy, R. M., Weedon, M. N., Hattersley, A. T., Hayward, C. & 11 othersMachann, J., Häring, H. U., Paul Franks, de Mutsert, R., Pearson, E., Stefan, N., Frayling, T. M., Allebrandt, K. V., Bell, J. D., Blakemore, A. I. & Yaghootkar, H., 2019, In : Diabetes. 68, 1, p. 207-219 13 p.

    Research output: Contribution to journalArticle

  34. Variation in the adiponutrin gene influences its expression and associates with obesity.

    Johansson, L., Hoffstedt, J., Parikh, H., Emma A Nilsson, Wabitsch, M., Bondeson, A-G., Jan Hedenbro, Tornqvist, H., Leif Groop & Martin Ridderstråle, 2006, In : Diabetes. 55, 3, p. 826-833

    Research output: Contribution to journalArticle

  35. Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation

    Johansson, H., Lukinius, A., Moberg, L., Lundgren, T., Berne, C., Foss, A., Felldin, M., Källén, R., Salmela, K., Tibe, A., Tufveson, G., Ekdahl, KN., Elgue, G., Korsgren, O. & Nilsson, B., 2005, In : Diabetes. 54, 6, p. 1755-1762

    Research output: Contribution to journalArticle

  36. Effect of Common Genetic Variants Associated with Type 2 Diabetes and Glycemic Traits on α- and β-cell Function and Insulin Action in Man.

    Jonsson, A., Ladenvall, C., Ahluwalia, T. S., Jasmina Kravic, Krus, U., Taneera, J., Isomaa, B., Tuomi, T., Erik Renström, Leif Groop & Valeriya Lyssenko, 2013, In : Diabetes. 62, 8, p. 2978-2983

    Research output: Contribution to journalArticle

  37. A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.

    Jonsson, A., Isomaa, B., Tuomi, T., Taneera, J., S Albert Salehi, Peter Nilsson, Leif Groop & Valeriya Lyssenko, 2009, In : Diabetes. 58, 10, p. 2409-2413

    Research output: Contribution to journalArticle

  38. Short-Term Exercise Training Does Not Stimulate Skeletal Muscle ATP Synthesis in Relatives of Humans With Type 2 Diabetes

    Kacerovsky-Bielesz, G., Chmelik, M., Charlotte Ling, Pokan, R., Szendroedi, J., Farukuoye, M., Kacerovsky, M., Schmid, A. I., Gruber, S., Wolzt, M., Moser, E., Pacini, G., Smekal, G., Leif Groop & Roden, M., 2009, In : Diabetes. 58, 6, p. 1333-1341

    Research output: Contribution to journalArticle

  39. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat

    Kaldunski, M. L., Jia, S., Geoffrey, R., Basken, J., Prosser, S., Kansra, S., Mordes, J. P., Åke Lernmark, Wang, X. & Hessner, M. J., 2010, In : Diabetes. 59, 10, p. 2375-2385 11 p.

    Research output: Contribution to journalArticle

  40. Immunoglobulin from insulin-dependent diabetic children inhibits glucose-induced insulin release

    Kanatsuna, T., Baekkeskov, S., A. Lernmark & Ludvigsson, J., 1983 Jan 1, In : Diabetes. 32, 6 I, p. 520-524 5 p.

    Research output: Contribution to journalArticle

  41. Block in insulin release from column-perifused pancreatic β-cells induced by islet cell surface antibodies and complement

    Kanatsuna, T., A. Lernmark, Rubenstein, A. H. & Steiner, D. F., 1981 Jan 1, In : Diabetes. 30, 3, p. 231-234 4 p.

    Research output: Contribution to journalArticle

  42. Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant A 14-Cohort Meta-analysis

    Kanoni, S., Nettleton, J. A., Hivert, M-F., Ye, Z., van Rooij, F. J. A., Shungin, D., Sonestedt, E., Ngwa, J. S., Wojczynski, M. K., Lemaitre, R. N., Gustafsson, S., Anderson, J. S., Tanaka, T., Hindy, G., Saylor, G., Renstrom, F., Bennett, A. J., van Duijn, C. M., Florez, J. C., Fox, C. S. & 36 othersHofman, A., Hoogeveen, R. C., Houston, D. K., Hu, F. B., Jacques, P. F., Johansson, I., Lind, L., Liu, Y., McKeown, N., Ordovas, J., Pankow, J. S., Sijbrands, E. J. G., Syvanen, A-C., Uitterlinden, A. G., Yannakoulia, M., Zillikens, M. C., Wareham, N. J., Prokopenko, I., Bandinelli, S., Forouhi, N. G., Cupples, L. A., Loos, R. J., Hallmans, G., Dupuis, J., Langenberg, C., Ferrucci, L., Kritchevsky, S. B., McCarthy, M. I., Ingelsson, E., Borecki, I. B., Witteman, J. C. M., Marju Orho-Melander, Siscovick, D. S., Meigs, J. B., Paul Franks & Dedoussis, G. V., 2011, In : Diabetes. 60, 9, p. 2407-2416

    Research output: Contribution to journalArticle

  43. Recombinant glutamic acid decarboxylase (representing the single isoform expressed in human islets) detects IDDM-associated 64,000-Mr autoantibodies

    Karlsen, A. E., Hagopian, W. A., Petersen, J. S., Boel, E., Dyrberg, T., Grubin, C. E., Michelsen, B. K., Madsen, O. D. & Åke Lernmark, 1992 Jan 1, In : Diabetes. 41, 10, p. 1355-1359

    Research output: Contribution to journalArticle

  44. Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity

    Keildson, S., Fadista, J., Ladenvall, C., Hedman, A. K., Elgzyri, T., Small, K. S., Grundberg, E., Nica, A. C., Glass, D., Richards, J. B., Barrett, A., Nisbet, J., Zheng, H-F., Rönn, T., Ström, K., Eriksson, K-F., Prokopenko, I., Spector, T. D., Dermitzakis, E. T., Deloukas, P. & 6 othersMcCarthy, M. I., Rung, J., Leif Groop, Paul Franks, Lindgren, C. M. & Ola Hansson, 2014, In : Diabetes. 63, 3, p. 1154-1165

    Research output: Contribution to journalArticle

  45. The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History to the Progression from Multiple Autoantibodies to Type 1 Diabetes:A TEDDY Study Report: A TEDDY Study Report

    Krischer, J. P., Liu, X., Åke Lernmark, Hagopian, W. A., Rewers, M. J., She, J-X., Toppari, J., Ziegler, A-G., Akolkar, B. & TEDDY Study Group, 2017, In : Diabetes. 66, 12, p. 3122-3129

    Research output: Contribution to journalArticle

  46. Circulating fetuin - A and risk of type 2 diabetes: A mendelian randomization analysis

    Kröger, J., Meidtner, K., Stefan, N., Guevara, M., Kerrison, N. D., Ardanaz, E., Aune, D., Boeing, H., Dorronsoro, M., Dow, C., Fagherazzi, G., Franks, P. W., Freisling, H., Gunter, M. J., Huerta, J. M., Kaaks, R., Key, T. J., Khaw, K. T., Krogh, V., Kühn, T. & 23 othersMancini, F. R., Mattiello, A., Peter M. Nilsson, Olsen, A., Overvad, K., Palli, D., Quirós, J. R., Rolandsson, O., Sacerdote, C., Sala, N., Salamanca-Fernández, E., Sluijs, I., Spijkerman, A. M. W., Tjonneland, A., Tsilidis, K. K., Tumino, R., Van Der Schouw, Y. T., Forouhi, N. G., Sharp, S. J., Langenberg, C., Riboli, E., Schulze, M. B. & Wareham, N. J., 2018 Jun 1, In : Diabetes. 67, 6, p. 1200-1205 6 p.

    Research output: Contribution to journalArticle

  47. Decreased expression of heat shock protein 72 in skeletal muscle of patients with type 2 diabetes correlates with insulin resistance

    Kurucz, I., Morva, A., Vaag, A., Karl-Fredrik Eriksson, Huang, X., Leif Groop & Koranyi, L., 2002, In : Diabetes. 51, 4, p. 1102-1109

    Research output: Contribution to journalArticle